Results 131 to 140 of about 27,335,908 (329)

Extensive Direct Subcortical Cerebellum-Basal Ganglia Connections in Human Brain as Revealed by Constrained Spherical Deconvolution Tractography

open access: yesFrontiers in Neuroanatomy, 2016
The connections between the cerebellum and basal ganglia were assumed to occur at the level of neocortex. However evidences from animal data have challenged this old perspective showing extensive subcortical pathways linking the cerebellum with the basal
D. Milardi   +10 more
semanticscholar   +1 more source

The Basal Ganglia in Action [PDF]

open access: yesThe Neuroscientist, 2016
The basal ganglia (BG) are the major subcortical nuclei in the brain. Disorders implicating the BG are characterized by diverse symptoms, but it remains unclear what these symptoms have in common or how they can be explained by changes in the BG circuits.
openaire   +3 more sources

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

open access: yesAdvanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang   +15 more
wiley   +1 more source

Adult-onset isolated hemichorea revealing iatrogenic hypoparathyroidism and bilateral basal ganglia calcification

open access: yesAnnals of Indian Academy of Neurology, 2019
Isolated hemichorea (HC) in adults has a relatively restricted differential diagnosis including stroke of contralateral basal ganglia nuclei, nonketotic hyperglycemia, and basal ganglia toxoplasmosis in HIV infection.
Karan Desai   +3 more
doaj   +1 more source

A computational approach to the covert and overt deployment of spatial attention [PDF]

open access: yes, 2008
Popular computational models of visual attention tend to neglect the influence of saccadic eye movements whereas it has been shown that the primates perform on average three of them per seconds and that the neural substrate for the deployment of ...
Alexandre, Frédéric   +2 more
core   +2 more sources

Gd-based Contrast Enhancement of the Perivascular Spaces in the Basal Ganglia

open access: yesMagnetic Resonance in Medical Sciences, 2016
Purpose: In textbooks, the perivascular space (PVS) is described as non-enhancing after the intravenous administration of gadolinium-based contrast agent (IV-GBCA).
S. Naganawa   +3 more
semanticscholar   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

open access: yesAdvanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang   +9 more
wiley   +1 more source

Beyond Critical Period Learning: Striatal FoxP2 Affects the Active Maintenance of Learned Vocalizations in Adulthood. [PDF]

open access: yes, 2019
In humans, mutations in the transcription factor forkhead box P2 (FOXP2) result in language disorders associated with altered striatal structure. Like speech, birdsong is learned through social interactions during maturational critical periods, and it ...
Day, Nancy F   +3 more
core  

Motor Learning Mechanism on the Neuron Scale

open access: yes, 2014
Based on existing data, we wish to put forward a biological model of motor system on the neuron scale. Then we indicate its implications in statistics and learning.
Liu, Peilei, Wang, Ting
core   +1 more source

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