Results 11 to 20 of about 132,485 (264)

Spatio-temporal dynamics of large-scale electrophysiological networks during cognitive action control in healthy controls and Parkinson's disease patients

open access: yesNeuroImage, 2022
Among the cognitive symptoms that are associated with Parkinson's disease (PD), alterations in cognitive action control (CAC) are commonly reported in patients. CAC enables the suppression of an automatic action, in favor of a goal-directed one.
Joan Duprez   +11 more
doaj   +1 more source

Biases in facial and vocal emotion recognition in chronic schizophrenia

open access: yesFrontiers in Psychology, 2014
There has been extensive research on impaired emotion recognition in schizophrenia in the facial and vocal modalities. The literature points to biases toward non-relevant emotions for emotional faces but few studies have examined biases in emotional ...
Thibaut eDondaine   +11 more
doaj   +1 more source

Rodent models of impulsive–compulsive behaviors in Parkinson's disease: How far have we reached?

open access: yesNeurobiology of Disease, 2015
There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of behavioral addictions, which have been clinically defined as impulsive–compulsive behaviors (ICBs).
M. Angela Cenci   +3 more
doaj   +1 more source

The basal ganglia [PDF]

open access: yesTrends in Neurosciences, 1995
Augood SJ, Penney JB Jr, Friberg IK, Breakefield XO, Young AB, Ozelius LJ, Standaert DG: Expression of the early-onset torsion dystonia gene (DYT1) in human brain.Ann Neurol 1998, 43:669-673.Bejjani BP, Damier P, Arnulf I, Thivard L, Bonnet AM, Dormont D, Cornu P, Pidoux B, Samson Y, Agid Y.
openaire   +3 more sources

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

open access: yesNeurobiology of Disease, 2017
Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slow ...
Irene Sebastianutto   +2 more
doaj   +1 more source

The basal ganglia and apraxia [PDF]

open access: yesBrain, 1996
Ever since Liepmann's original descriptions at the beginning of the century apraxia has usually been attributed to damage confined to the cerebral cortex and/or cortico-cortical connecting pathways. However, there have been suggestions that apraxia can be due to deep subcortical lesions, which raises the question as to whether damage to the basal ...
P P, Pramstaller, C D, Marsden
openaire   +2 more sources

How ‘Basal' Are the Basal Ganglia? [PDF]

open access: yesBrain, Behavior and Evolution, 2013
years ago [Erwin et al., 2011], did not merely have a substantial rostral brain, but specifically a telencephalon, an elaborate set of forebrain structures hitherto recognized only in vertebrates. The set of structures that Strausfeld and Hirth [2013a] identify as the arthropod homolog of the basal ganglia is the central complex, a group of median ...
openaire   +2 more sources

Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion

open access: yesNeurobiology of Disease, 2016
Mice with striatal 6-hydroxydopamine (6-OHDA) lesions are widely used as a model to study the effects of neurorestorative, symptomatic, or antidyskinetic treatments for Parkinson's disease (PD).
Francesco Bez   +2 more
doaj   +1 more source

Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists

open access: yesNeurobiology of Disease, 2016
Rodent models of l-DOPA-induced dyskinesia (LID) are essential to investigate pathophysiological mechanisms and treatment options. Ratings of abnormal involuntary movements (AIMs) are used to capture both qualitative and quantitative features of ...
Irene Sebastianutto   +3 more
doaj   +1 more source

Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia

open access: yesNeurobiology of Disease, 2004
We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa (l-DOPA)-induced dyskinesia and Parkinson disease (PD).
Christine Konradi   +7 more
doaj   +1 more source

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