Results 21 to 30 of about 135,658 (261)
Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia
Neurobiology of Disease, 2004 We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa (l-DOPA)-induced dyskinesia and Parkinson disease (PD).
Christine Konradi +7 more
doaj +1 more source
Neurobiology of Disease, 2011 6-Hydroxydopamine (6-OHDA) lesions are being used in the mouse for basic research on Parkinson's disease and L-DOPA-induced dyskinesia. We set out to compare unilateral lesion models produced by intrastriatal or intramesencephalic injections of a fixed 6-
Veronica Francardo +5 more
doaj +1 more source
Neurobiology of Disease, 2009 Serotonin has been postulated to play a role in the transplant-induced involuntary movements that occur following intrastriatal grafts of ventral mesencephalic tissue in the treatment of Parkinson's disease.
Emma Louise Lane +2 more
doaj +1 more source
Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease
Neurobiology of Disease, 2008 The observation that neural grafts can induce dyskinesias has severely hindered the development of a transplantation therapy for Parkinson's disease (PD).
E.L. Lane +4 more
doaj +1 more source
Neurobiology of Disease, 2006 Intrastriatal transplants of embryonic ventral mesencephalon can cause dyskinesia in patients with Parkinson's disease (PD). We assessed the impact of transplant size on the development of graft-induced dyskinesia.
E.L. Lane +3 more
doaj +1 more source
Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model
Neurobiology of Disease, 2016 Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in autoradiograms from 6-hydroxydopamine (6-OHDA) rat. In both species, acute levodopa administration was
Renata P. Lerner +6 more
doaj +1 more source
Autoimmune basal ganglia encephalitis associated with anti-recoverin antibodies: A case report
eNeurologicalSci, 2021 Autoimmune basal ganglia encephalitis causes neurological symptoms such as parkinsonism associated with basal ganglia lesions. Here, we report a case of autoimmune basal ganglia encephalitis without retinal lesions or malignancy harboring anti-recoverin ...
Yuki Kitazaki +8 more
doaj +1 more source
The Basal Ganglia in Action [PDF]
The Neuroscientist, 2016 The basal ganglia (BG) are the major subcortical nuclei in the brain. Disorders implicating the BG are characterized by diverse symptoms, but it remains unclear what these symptoms have in common or how they can be explained by changes in the BG circuits.
openaire +2 more sources
PDZD8 is not the ‘functional ortholog’ of Mmm1, it is a paralog [version 1; referees: 2 approved]
F1000Research, 2018 Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells.
Jeremy G. Wideman +3 more
doaj +1 more source
Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children
Brain Sciences, 2020 Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states.
Justyna Paprocka +3 more
doaj +1 more source