Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits [PDF]
, 2016 Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD).
Bucklin, Mark +5 more
core +1 more source
Neurobiology of Disease, 2006 Intrastriatal transplants of embryonic ventral mesencephalon can cause dyskinesia in patients with Parkinson's disease (PD). We assessed the impact of transplant size on the development of graft-induced dyskinesia.
E.L. Lane +3 more
doaj +1 more source
Temporal discrimination: Mechanisms and relevance to adult-onset dystonia [PDF]
, 2017 Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as ...
Beck, Rebecca +7 more
core +1 more source
Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Prevalence and temporal dynamics of transient oscillations in the beta frequency band (15 to 35 Hz), referred to as β bursts, are correlated with motor performance.
H. Cagnan +11 more
semanticscholar +1 more source
Autoimmune basal ganglia encephalitis associated with anti-recoverin antibodies: A case report
eNeurologicalSci, 2021 Autoimmune basal ganglia encephalitis causes neurological symptoms such as parkinsonism associated with basal ganglia lesions. Here, we report a case of autoimmune basal ganglia encephalitis without retinal lesions or malignancy harboring anti-recoverin ...
Yuki Kitazaki +8 more
doaj +1 more source
Increased bradykinesia in Parkinson’s disease with increased movement complexity: elbow flexion-extension movements [PDF]
, 2008 The present research investigates factors contributing to bradykinesia in the control of simple and complex voluntary limb movement in Parkinson’s disease (PD) patients.
Geelen, J.A.G. +3 more
core +4 more sources
Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model
Neurobiology of Disease, 2016 Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in autoradiograms from 6-hydroxydopamine (6-OHDA) rat. In both species, acute levodopa administration was
Renata P. Lerner +6 more
doaj +1 more source
Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children
Brain Sciences, 2020 Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states.
Justyna Paprocka +3 more
doaj +1 more source
The basal ganglia, the ideal machinery for the cost-benefit analysis of action plans [PDF]
, 2013 Basal ganglia dysfunction causes profound movement disorders, often attributed to imbalance between direct and indirect pathway activity in the sensorimotor basal ganglia.
Hwang, Eun Jung
core +2 more sources
PDZD8 is not the ‘functional ortholog’ of Mmm1, it is a paralog [version 1; referees: 2 approved]
F1000Research, 2018 Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells.
Jeremy G. Wideman +3 more
doaj +1 more source