Results 41 to 50 of about 246,657 (284)

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

The causal interaction in human basal ganglia

Scientific Reports, 2021
The experimental study of the human brain has important restrictions, particularly in the case of basal ganglia, subcortical centers whose activity can be recorded with fMRI methods but cannot be directly modified.
Clara Rodriguez-Sabate, Albano Gonzalez, Juan Carlos Perez-Darias, Ingrid Morales, Manuel Rodriguez   +4 more
doaj   +1 more source

How Laminar Frontal Cortex and Basal Ganglia Circuits Interact to Control Planned and Reactive Saccades [PDF]

, 2000
The basal ganglia and frontal cortex together allow animals to learn adaptive responses that acquire rewards when prepotent reflexive responses are insufficient.
Brown, Joshua, Bullock, Daniel, Grossberg, Stephen   +2 more
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment

npj Parkinson's Disease
Dopamine replacement therapy for Parkinson’s disease can induce impulsive-compulsive behaviours (ICBs). Here we compare the D2/3 agonist ropinirole and L-DOPA, given alone or combined, with regard to their potential to induce ICBs in rats sustaining ...
Mirjam Wolfschlag, Elena Espa, Katrine Skovgård, Pär Halje, Maria Angela Cenci   +4 more
doaj   +1 more source

Exploring the cognitive and motor functions of the basal ganglia: An integrative review of computational cognitive neuroscience models

Frontiers in Computational Neuroscience, 2013
Many computational models of the basal ganglia have been proposed over the past twenty-five years. While computational neuroscience models have focused on closely matching the neurobiology of the basal ganglia, computational cognitive neuroscience models
Sebastien eHelie, Srinivasa eChakravarthy, Ahmed A. Moustafa   +2 more
doaj   +1 more source

Regional differences in the coupling between resting cerebral blood flow and metabolism may indicate action preparedness as a default state. [PDF]

, 2008
Although most functional neuroimaging studies examine task effects, interest intensifies in the "default" resting brain. Resting conditions show consistent regional activity, yet oxygen extraction fraction constancy across regions.
Alavi, Abass, Greenberg, Joel H, Gur, Raquel E, Gur, Ruben C, Ragland, J Daniel, Reivich, Martin   +5 more
core   +2 more sources

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source

Childhood Adversity is Associated with Left Basal Ganglia Dysfunction During Reward Anticipation in Adulthood [PDF]

, 2009
Background: Childhood adversity increases the risk of psychopathology, but the neurobiological mechanisms underlying this vulnerability are not well-understood.
Anda, Anisman, Avram J. Holmes, Beck, Bjork, Blumenthal, Bremner, Cabib, Carlson, Chapman, Charney, Daniel G. Dillon, Deichmann, Diego A. Pizzagalli, Dillon, Dong, Drevets, Dube, Dube, Epstein, Fawcett, First, Fischl, Frank, Gabbay, George, Gladstone, Guyer, Harkness, Heim, Jeffrey L. Birk, Kalinichev, Karlen Lyons-Ruth, Kaufman, Knutson, Lumley, Lyons-Ruth, Lyons-Ruth, Martin, Matthews, Meyer, Miller, Nancy Brooks, Navalta, Nelson, Norris, Pizzagalli, Pollak, Pryce, Radloff, Samanez-Larkin, Schott, Smith, Starkstein, Strauss, Tae, Teicher, Tomer, Vataja, Volkow, Watson, Widom, Willner   +62 more
core   +1 more source

Quantity and Volume of Perivascular Spaces Are Inversely Associated With Multiple Sclerosis Relative to Cerebrovascular Disease and Migraine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS, such as cerebrovascular disease.
Elle M. Levit, Elizabeth A. Horwath, Daniel L. Schwartz, Lisa C. Silbert, Russell T. Shinohara, Andrew J. Solomon   +5 more
wiley   +1 more source