Results 41 to 50 of about 26,837,893 (264)
Off-Target 18F-AV-1451 Binding in the Basal Ganglia Correlates with Age-Related Iron Accumulation
Journal of Nuclear Medicine, 2018 Off-target binding in the basal ganglia is commonly observed in the 18F-AV-1451 PET studies of the elderly. We sought to investigate the relationship between this phenomenon in the basal ganglia and iron accumulation using iron-sensitive R2* MRI. Methods:
J. Choi +6 more
semanticscholar +1 more source
Acta Neuropathologica Communications, 2018 Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar ...
Violetta Refolo +11 more
doaj +1 more source
Mean-field modeling of the basal ganglia-thalamocortical system. I. Firing rates in healthy and parkinsonian states [PDF]
J. Theor. Biol. 257: 642-663 (2009), 2018 Parkinsonism leads to various electrophysiological changes in the basal ganglia-thalamocortical system (BGTCS), often including elevated discharge rates of the subthalamic nucleus (STN) and the output nuclei, and reduced activity of the globus pallidus external segment (GPe).
arxiv +1 more source
Frontiers in Computational Neuroscience, 2013 Many computational models of the basal ganglia have been proposed over the past twenty-five years. While computational neuroscience models have focused on closely matching the neurobiology of the basal ganglia, computational cognitive neuroscience models
Sebastien eHelie +2 more
doaj +1 more source
The causal interaction in human basal ganglia
Scientific Reports, 2021 The experimental study of the human brain has important restrictions, particularly in the case of basal ganglia, subcortical centers whose activity can be recorded with fMRI methods but cannot be directly modified.
Clara Rodriguez-Sabate +4 more
doaj +1 more source
The external pallidum: think locally, act globally [PDF]
arXiv, 2021 The globus pallidus (GPe) of the basal ganglia has been underappreciated for decades due to poor understanding of its cells and circuits. The advent of molecular tools has sparked a resurgence in interest in the GPe. Here, we review a recent flurry of publications that has unveiled the complexity of the molecular landscape and cellular composition ...
arxiv
NeuroImage, 2022 Among the cognitive symptoms that are associated with Parkinson's disease (PD), alterations in cognitive action control (CAC) are commonly reported in patients. CAC enables the suppression of an automatic action, in favor of a goal-directed one.
Joan Duprez +11 more
doaj
Bidirectional Control of Absence Seizures by the Basal Ganglia: A Computational Evidence [PDF]
, 2014 Absence epilepsy is believed to be associated with the abnormal interactions between the cerebral cortex and thalamus. Besides the direct coupling, anatomical evidence indicates that the cerebral cortex and thalamus also communicate indirectly through an important intermediate bridge--basal ganglia.
arxiv +1 more source
, 2020 AbstractThe basal ganglia include the striatum (caudate, putamen, and ventral striatum) which receive from all cortical areas, and which project via the globus pallidus and substantia nigra back to the neocortex. The basal ganglia are implicated in stimulus-response habit learning, which may be provided by a reinforcement learning signal received by ...
openaire +1 more source
Thalamocortical contribution to solving credit assignment in neural systems [PDF]
arXiv, 2021 Animal brains evolved to optimize behavior in dynamically changing environments, selecting actions that maximize future rewards. A large body of experimental work indicates that such optimization changes the wiring of neural circuits, appropriately mapping environmental input onto behavioral outputs.
arxiv