Results 11 to 20 of about 70,366 (259)

Optimized AAV capsids for basal ganglia diseases show robust potency and distribution [PDF]

Nature Communications
Huntington’s disease and other disorders of the basal ganglia create challenges for biomolecule-based medicines given the poor accessibility of these deep brain structures following intracerebral or intravascular delivery.
D. E. Leib, Y. H. Chen, L. Tecedor, P. T. Ranum, M. S. Keiser, B. C. Lewandowski, E. M. Carrell, S. Arora, I. Huerta-Ocampo, D. Lai, C. M. Fluta, C. Cheng, X. Liu, B. L. Davidson   +13 more
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NEUROSURGICAL TREATMENT OF BASAL GANGLIA DISEASES

The Turkish Journal of Pediatrics, 1964
N Avmann, T Derinkoek
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The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

eLife, 2021
Human reproduction is controlled by ~2000 hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Here, we report the discovery and characterization of additional ~150,000–200,000 GnRH-synthesizing cells in the human basal ganglia and basal forebrain.
Katalin Skrapits, Miklós Sárvári, Imre Farkas, Balázs Göcz, Szabolcs Takács, Éva Rumpler, Viktória Váczi, Csaba Vastagh, Gergely Rácz, András Matolcsy, Norbert Solymosi, Szilárd Póliska, Blanka Tóth, Ferenc Erdélyi, Gábor Szabó, Michael D Culler, Cecile Allet, Ludovica Cotellessa, Vincent Prévot, Paolo Giacobini, Erik Hrabovszky   +20 more
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Extrastriatal dopaminergic circuits of the basal ganglia

Frontiers in Neuroanatomy, 2010
The basal ganglia are comprised of the striatum, the external and internal segment of the globus pallidus (GPe and GPi, respectively), the subthalamic nucleus (STN), and the substantia nigra pars compacta and reticulata (SNc and SNr, respectively ...
Karen Suzanne Rommelfanger, Thomas eWichmann, Thomas eWichmann   +2 more
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18F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging evaluation of chorea

Neurology International, 2018
Chorea is thought to be caused by deactivation of the indirect pathway in the basal ganglia circuit. However, few imaging studies have evaluated the basal ganglia circuit in actual patients with chorea.
Nobuyuki Ishii, Hitoshi Mochizuki, Miyuki Miyamoto, Yuka Ebihara, Kazutaka Shiomi, Masamitsu Nakazato   +5 more
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Jules Bernard Luys: from a description of the subthalamic nucleus to hypnotism [PDF]

Arquivos de Neuro-Psiquiatria, 2020
The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson’s disease, are well known.
Alex Tiburtino MEIRA, Anieli Fagiani PRODÓSSIMO, Gabriel Sampaio FROEHNER, Gustavo Leite FRANKLIN, Murilo Sousa DE MENESES, Renato Puppi MUNHOZ, Hélio Afonso Ghizoni TEIVE   +6 more
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Immunological causes of obsessive-compulsive disorder: is it time for the concept of an “autoimmune OCD” subtype?

Translational Psychiatry, 2022
Obsessive-compulsive disorder (OCD) is a highly disabling mental illness that can be divided into frequent primary and rarer organic secondary forms. Its association with secondary autoimmune triggers was introduced through the discovery of Pediatric ...
Dominique Endres, Thomas A. Pollak, Karl Bechter, Dominik Denzel, Karoline Pitsch, Kathrin Nickel, Kimon Runge, Benjamin Pankratz, David Klatzmann, Ryad Tamouza, Luc Mallet, Marion Leboyer, Harald Prüss, Ulrich Voderholzer, Janet L. Cunningham, ECNP Network Immuno-NeuroPsychiatry, Katharina Domschke, Ludger Tebartz van Elst, Miriam A. Schiele   +18 more
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Cerebellar and basal ganglia structural connections in humans: Effect of aging and relation with memory and learning

Frontiers in Aging Neuroscience, 2023
IntroductionThe cerebellum and basal ganglia were initially considered anatomically distinct regions, each connected via thalamic relays which project to the same cerebral cortical targets, such as the motor cortex. In the last two decades, transneuronal
Vineeth Radhakrishnan, Cecile Gallea, Romain Valabregue, Syam Krishnan, Chandrasekharan Kesavadas, Bejoy Thomas, Praveen James, Ramshekhar Menon, Asha Kishore, Asha Kishore   +9 more
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Brain Magnetic Resonance Imaging Characteristics of Anti-Leucine-Rich Glioma-Inactivated 1 Encephalitis and Their Clinical Relevance: A Single-Center Study in China

Frontiers in Neurology, 2021
Objective: To characterize the magnetic resonance imaging (MRI) features of anti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis and explore their clinical relevance.Methods: Patients with anti-LGI1 encephalitis who underwent MRI at our center were
Xiali Shao, Xiali Shao, Siyuan Fan, Huan Luo, Ting Yat Wong, Weihong Zhang, Hongzhi Guan, Anqi Qiu, Anqi Qiu   +8 more
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The imaging features of perivascular spaces in differentiation of cerebral small vessel disease and multiple sclerosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the imaging features differences of perivascular spaces(PVS) between cerebral small vessel disease(cSVD) and multiple sclerosis(MS).
Xue⁃hong HUANG, Xiao⁃dong CHEN, San⁃xin LIU, Si⁃yuan LIAO , Bing⁃jun ZHANG, Zheng⁃qi LU   +5 more
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