Results 21 to 30 of about 70,366 (259)

Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease

NeuroImage: Clinical, 2017
The ability to inhibit automatic versus voluntary saccade commands in demanding situations can be impaired in neurodegenerative diseases such as Huntington's disease (HD).
Israel Vaca-Palomares, Brian C. Coe, Donald C. Brien, Aurelio Campos-Romo, Douglas P. Munoz, Juan Fernandez-Ruiz   +5 more
doaj   +1 more source

Abnormal eye movements in three types of chorea

Arquivos de Neuro-Psiquiatria
Chorea is an abnormal movement characterized by a continuous flow of random muscle contractions. This phenomenon has several causes, such as infectious and degenerative processes. Chorea results from basal ganglia dysfunction.
Tiago Attoni, Rogério Beato, Serge Pinto, Francisco Cardoso   +3 more
doaj   +1 more source

Regional Distributions of Iron, Copper and Zinc and Their Relationships With Glia in a Normal Aging Mouse Model

Frontiers in Aging Neuroscience, 2019
Microglia and astrocytes can quench metal toxicity to maintain tissue homeostasis, but with age, increasing glial dystrophy alongside metal dyshomeostasis may predispose the aged brain to acquire neurodegenerative diseases.
Azhaar Ashraf, Christos Michaelides, Thomas A. Walker, Antigoni Ekonomou, Maria Suessmilch, Achvini Sriskanthanathan, Semhar Abraha, Adam Parkes, Harold G. Parkes, Kalotina Geraki, Po-Wah So   +10 more
doaj   +1 more source

Increased Basal Ganglia Modulatory Effective Connectivity Observed in Resting-State fMRI in Individuals With Parkinson’s Disease

Frontiers in Aging Neuroscience, 2022
Alterations to interactions between networked brain regions underlie cognitive impairment in many neurodegenerative diseases, providing an important physiological link between brain structure and cognitive function.
Nicholas J. Wapstra, Micah Ketola, Shelby Thompson, Adel Lee, Tara Madhyastha, Thomas J. Grabowski, Thomas J. Grabowski, Andrea Stocco   +7 more
doaj   +1 more source

Early Amyloid Formation and Neuroinflammatory Response in a Bigenic Mouse Model Expressing Human α-Synuclein and Aβ

Parkinson's Disease
Protein aggregation is a hallmark of several neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease and dementia with Lewy bodies.
Radhika Thakore, Markus Aldén, Nadja Gustavsson, Lukas Danielson, Lívia Lins, Jorge Domínguez Sánchez, Ana Rosenthal Arensburg, Agnes Paulus, Iran Augusto Neves da Silva, Valeriia Skoryk, Rakez Kayed, Gunnar K. Gouras, Tomas Deierborg, Andreas Heuer, Sabine C. Konings, Oxana Klementieva   +15 more
doaj   +1 more source

Bilateral Basal Ganglia Calcification: Fahr's Disease [PDF]

Cureus, 2019
Fahr's disease/syndrome is a condition defined as bilateral striato-pallido-dentate calcinosis, a neurodegenerative disease with radiological findings of symmetrical and bilateral idiopathic calcifications of the cerebellum, periventricular white matter, and basal ganglia. Clinical correlation with radiological and a calcium metabolism panel is crucial
Ooi, Hsein Wei, Er, Chaozer, Hussain, Ikram, Kuthiah, Navin, Meyyur Aravamudan, Veeraraghavan   +4 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Fahr’s Syndrome and Neuropsychiatric Symptoms: Differential Diagnosis in Neuropsychiatry

Acta Médica Portuguesa, 2019
N/a.
Tomás Teodoro, Renato Oliveira
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Neuroanatomical correlates of intelligence in healthy young adults: the role of basal ganglia volume.

PLoS ONE, 2014
BackgroundIn neuropsychiatric diseases with basal ganglia involvement, higher cognitive functions are often impaired. In this exploratory study, we examined healthy young adults to gain detailed insight into the relationship between basal ganglia volume ...
Cosima Rhein, Christiane Mühle, Tanja Richter-Schmidinger, Panagiotis Alexopoulos, Arnd Doerfler, Johannes Kornhuber   +5 more
doaj   +1 more source