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Insulin Degludec, The New Generation Basal Insulin or Just another Basal Insulin?

Clinical Medicine Insights: Endocrinology and Diabetes, 2012
The advances in recombinant DNA technology have led to an improvement in the properties of currently available long-acting insulin analogs. Insulin degludec, a new generation ultra-long-acting basal insulin, currently in phase 3 clinical trials, has a ...
Sami N. Nasrallah, L. Raymond Reynolds
doaj   +4 more sources

Healthcare Resource Utilization and Costs Related to Falls and Fractures Among People With Type 2 Diabetes Receiving Basal Insulin: The FRAGILE Study [PDF]

Journal of Health Economics and Outcomes Research
# Background The association between falls or fall-related fractures and hypoglycemia in people with type 2 diabetes is well established. Insulin treatment is associated with an increased risk of hypoglycemia, which is compounded in people of older age ...
Guillermo E. Umpierrez, Elizabeth K. Pogge, Xuan Li, Ronald Preblick, Jasvinder Gill, Naushira Pandya   +5 more
doaj   +2 more sources

Clinical Outcomes of Switching U-100 Intermediate or Basal Insulin to U-200 Insulin Degludec or U-300 Insulin Glargine [PDF]

Journal of Primary Care & Community Health
Introduction: Basal and intermediate insulin is available as U-100 (glargine, determir, NPH) or ultra-long-acting (ULA) U-200 (degludec) or U-300 (glargine).
Natalie Rosario, Cami Hunger, Allison Pettijohn, K’bria Whaley, Andrea Pabon, Valeria Hohl, Bernadette Asias-Dinh, Jodie Gee, Joshua Wollen   +8 more
doaj   +2 more sources

Evaluating Patient and Provider Preferences for a Once-Weekly Basal Insulin in Adults with Type 2 Diabetes [PDF]

Patient Preference and Adherence
David Kerr,1 Jigar Ramesh Rajpura,2 Tarlan Namvar3 1Center for Health Systems Research, Sutter Health, Santa Barbara, CA, USA; 2Department of US Health Economic and Outcomes Research – Rare Disease Portfolio, Novo Nordisk Inc, Plainsboro, NJ, USA ...
Kerr D, Rajpura JR, Namvar T
doaj   +2 more sources

Effect of the Concomitant Use of Subcutaneous Basal Insulin and Intravenous Insulin Infusion in the Treatment of Severe Hyperglycemic Patients [PDF]

Endocrinology and Metabolism, 2022
Background No consensus exists regarding the early use of subcutaneous (SC) basal insulin facilitating the transition from continuous intravenous insulin infusion (CIII) to multiple SC insulin injections in patients with severe hyperglycemia other than ...
Yejee Lim, Jung Hun Ohn, Joo Jeong, Jiwon Ryu, Sun-wook Kim, Jae Ho Cho, Hee-Sun Park, Hye Won Kim, Jongchan Lee, Eun Sun Kim, Nak-Hyun Kim, You Hwan Jo, Hak Chul Jang   +12 more
doaj   +1 more source

Open questions on basal insulin therapy in T2D: a Delphi consensus. [PDF]

Acta Diabetol
Delphi Board, Buzzetti R, Candido R, Esposito K, Giaccari A, Mannucci E, Nicolucci A, Russo GT.   +7 more
europepmc   +3 more sources

Effect of basal insulin therapy with glargine U300 versus basal bolus insulin therapy in hospitalized patients with type 2 diabetes. Real-world study from India

Clinical Diabetology, 2021
Background. Basal-bolus insulin therapy is the most widely accepted method of glycemic control in non-critically ill patients with T2DM. In this regimen glargine U100 is the most commonly used basal insulin.
Asis Mitra, Saswati Ray, Sushma Jayan
doaj   +1 more source

Observational study of the association of first insulin type in uncontrolled type 2 diabetes with macrovascular and microvascular disease [PDF]

, 2012
<p>Aims: To compare the risk of vascular disease, HbA1c and weight change, between first prescribed insulins in people with type 2 diabetes.</p> <p>Methods: People included in THIN United Kingdom primary care record database who ...
A Wright, Alex D. McMahon, AS Levey, AS Levey, Dawn Carroll, GC Hall, GC Hall, Gillian C. Hall, H Yki-Jarvinen, HU Janka, J Rosenstock, JD Lewis, M Calvert, MC Riddle, MC Riddle, P Home, Philip D. Home, RG Bretzel, RR Holman, RR Holman, TK Schramm, Xin-Liang Ma   +21 more
core   +9 more sources

Basal Insulin Reduces Glucose Variability and Hypoglycaemia Compared to Premixed Insulin in Type 2 Diabetes Patients: A Study Based on Continuous Glucose Monitoring Systems

Frontiers in Endocrinology, 2022
AimsTo examine the glycaemic variability and safety of basal and premixed insulin by using continuous glucose monitoring (CGM) systems.Methods393 patients with type 2 diabetes mellitus (T2DM) treated with basal or premixed insulin for more than 3 months ...
Huiying Wang, Yunting Zhou, Yuming Wang, Tingting Cai, Yun Hu, Ting Jing, Bo Ding, Xiaofei Su, Huiqin Li, Jianhua Ma   +9 more
doaj   +1 more source

Effect of Insulin Plant (Costus igneus) Leaf Powder in Broiler Chickens (Gallus galluus domisticus)

Diversitas Journal, 2023
This experiment was conducted to evaluate the effects of insulin plant leaf powder in broiler chickens. One hundred (100) chicks of the same age and random sexes were purchased from the local agrivet supplier and were used in the study.
Carla M Bagunoc, Amalia A. Royo, Risa M. Magalang   +2 more
doaj   +1 more source