Results 131 to 140 of about 365,960 (349)

Optimizing Basal Insulin Dosing [PDF]

open access: yesThe Journal of Pediatrics, 2019
Rayhan A, Lal, David M, Maahs
openaire   +2 more sources

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung   +7 more
wiley   +1 more source

A retrospective database analysis of insulin use patterns in insulin-naïve patients with type 2 diabetes initiating basal insulin or mixtures

open access: yesPatient Preference and Adherence, 2010
Machaon MK Bonafede1, Anupama Kalsekar2, Manjiri Pawaskar2, Kimberly M Ruiz3, Amelito M Torres3, Karen R Kelly2, Suellen M Curkendall31Thomson Reuters Inc, Cambridge, Massachusetts, USA; 2Eli Lilly and Company, Indianapolis, Indiana, USA; 3Thomson ...
Machaon MK Bonafede   +3 more
doaj  

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

open access: yesArthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler   +8 more
wiley   +1 more source

Insulin detemir - a novel basal insulin

open access: yesDiabetologia Croatica, 2003
Insulin detemir is a soluble long-acting insulin analogue developed to provide low, constant, and reproducible plasma insulin supply for up to 24 hours. Acylation of a 14-carbon chain fatty acid (myristic acid) to the lysine residue at position B29 of the insulin molecule results in delayed absorption due to both increased self-association at the ...
Pavlić-Renar, Ivana   +2 more
openaire   +2 more sources

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals with Type 2 Diabetes

open access: yesArthritis Care &Research, Accepted Article.
Objective Knee osteoarthritis (OA) commonly affects individuals with Type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

Evidence review : liraglutide for the treatment of type 2 diabetes [PDF]

open access: yes, 2011
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of liraglutide in the treatment of type 2 diabetes mellitus, based upon the manufacturer’s submission to the National Institute
Cummins, E. (Ewen)   +4 more
core  

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

open access: yesAdvanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han   +17 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

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