Results 91 to 100 of about 6,603,883 (279)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Sources and significance of variation in basal, summit and maximal metabolic rates in birds
Current Zoology, 2010 The rates at which birds use energy may have profound effects on fitness, thereby influencing physiology, behavior, ecology and evolution. Comparisons of standardized metabolic rates (e.g., lower and upper limits of metabolic power output) present a ...
Andrew E. MCKECHNIE, David L. SWANSON
doaj
National Journal of Physiology, Pharmacy and Pharmacology, 2019 Background: Obesity has become a major global problem leading to diabetes, hypertension, and metabolic syndrome. Aims and Objectives: The aim of this study was to assess the association between body fat percentage (BF%) and cardiac workload by rate ...
Anita Teli +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
[Calculating the basal metabolic rate and severe and morbid obesity]
, 2001 The aim of this study was to evaluate the currently available predictive equations for basal metabolic rate (BMR) in subjects with obesity class II and III, and to assess the contribution by the components of a two-compartment model of body composition ...
Bürgi, U, Diem, P, Müller, B, Merk, S
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
basal metabolic rate (BMR) data for phylogenetic temperature study
, 2018 basal metabolic rate data collected as change in carbon dioxide. for 44 species of drosophila with the species body size as wing length as a proxy.
katherine roberts (5011922) +2 more
core +1 more source
Здоров’я, спорт, реабілітаціяBackground and purpose This study investigates age-related changes in central adiposity, body composition, and basal metabolic rate in adult males residing in the Delhi region, emphasizing their implications for physical activity interventions aimed at ...
Kanaan Ibrahim Nawfal +3 more
doaj +3 more sources