Plasma metabolites reflect seasonally changing metabolic processes in a long-distance migrant shorebird (Calidris canutus) [PDF]
Migrant birds have tightly scheduled annual cycles consisting of several distinct life cycle (sub-)stages such as reproduction, migration, moult and overwintering, each of which have specific metabolic requirements (e.g., fattening during migration ...
Jenni, Lukas, +2 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Basal metabolic rate and risk of multiple sclerosis: a Mendelian randomization study [PDF]
Chunxin Liu +5 more
openalex +1 more source
The ecological impact of different mechanisms of chronic sub-lethal toxicity on feeding and respiratory physiology [PDF]
Sub-lethal toxicity tests, such as the scope-for-growth test, reveal simple relationships between measures of contaminant concentration and effect on respiratory and feeding physiology.
Willows, R.
core
Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial [PDF]
Introduction Evening-time exercise is a frequent cause of severe hypoglycemia in type 1 diabetes, fear of which deters participation in regular exercise.
Campbell, Matthew +7 more
core +4 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A comparison of methods to evaluate energy expenditure of incubating wandering albatrosses [PDF]
Measurements of incubation energetics can vary depending on the method used to measure metabolism of an incubating bird. Therefore, we evaluated the energy expenditure of six male and four female wandering albatrosses (Diomedea exulans Linnaeus) using ...
Costa, D P +2 more
core +1 more source
Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells. [PDF]
Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of malignancies including high grade serous ovarian cancer (HGSC).
Aspuria, Paul-Joseph P +6 more
core +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Phenotypic plasticity of metabolic rate in an afrotropical bird species (Euplectes orix) across a temperature gradient [PDF]
Avian species are known to have the capacity to respond to environmental changes through physiological adjustments. The process whereby organisms adjust their phenotype without genetic change is termed phenotypic plasticity and it is mostly observed to ...
Van de Ven, Tanja Maria Francisca Nicole
core +1 more source

