Results 61 to 70 of about 469,471 (280)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Determinação da taxa metabólica basal em cutias, Dasyprocta azarae, por calorimetria indireta Determination of the basal metabolic rate in agoutis, Dasyprocta azarae, by indirect calorimetry

Pesquisa Veterinária Brasileira, 2010
A melhor ferramenta para comparação fisiológica entre organismos diferentes é a taxa metabólica basal, inter-relação fundamental que existe entre todos os seres vivos.
Harald F.V. Brito, Rogério R. Lange, José R. Pachaly, Ivan Deconto   +3 more
doaj   +1 more source

Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. [PDF]

, 2017
Disruption of hepatocyte growth hormone (GH) signaling through disruption of Jak2 (JAK2L) leads to fatty liver. Previously, we demonstrated that development of fatty liver depends on adipocyte GH signaling.
Camporez, João Paulo G, Corbit, Kevin C, Deo, Rahul C, Edmunds, Lia R, Erion, Derek M, Jurczak, Michael J, Perry, Rachel J, Shulman, Gerald I, Tran, Jennifer L, Vera, Nicholas B, Weiss, Ethan J   +10 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Novel insights into the cardio-protective effects of FGF21 in lean and obese rat hearts [PDF]

, 2014
Aims: Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease.
A Beenken, A Kharitonenkov, A Planavila, A Romero-Corral, A Sharma, AD Attie, AK Bose, Bee K. Tan, BK Tan, C Valina, C Yang, D Morabito, DJ Hausenloy, DR Riddell, E Braunwald, Edward W. Hillhouse, Emilio Hirsch, FM Fisher, G Nanayakkara, GC Rodrigo, GD Lopaschuk, H Jiao, H Li, Harpal S. Randeva, J Diaz-Delfin, J Mair, J Yie, J Yie, Jing Chen, JP Bertinchant, L Timmers, LC Clavijo, M Mraz, Manjunath Ramanjaneya, MC Mendoza, Muhammad F. Bari, N Shimizu, PK Shah, R Adya, R Mitra, Raghu Adya, S Doroudgar, S Kenchaiah, S Yusuf, SQ Liu, SQ Liu, Sunil K. Bhudia, T Matsui, T Nishimura, T Thim, T Uebanso, V Lionetti, Vanlata Patel, Y Ogawa, Y Wang   +54 more
core   +8 more sources

Avian Song Complexity is Associated With High Field Metabolic Rate [PDF]

, 2006
Question: Is the production of bird song costly? Analyses of oxygen consumption during singing provided conflicting results. Data studied: Data on 28 passerine species with quantitative information on song complexity and field metabolic rate, which ...
Garamszegi, László Zsolt, Moller, Anders Pape, Moreno, Juan   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental study

Molecular Metabolism, 2018
Objectives: The laboratory mouse is presently the most common model for examining mechanisms of human physiology and disease. Housing temperatures can have a large impact on the outcome of such experiments and on their translatability to the human ...
Alexander W. Fischer, Barbara Cannon, Jan Nedergaard   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A comparison of methods to evaluate energy expenditure of incubating wandering albatrosses [PDF]

, 2001
Measurements of incubation energetics can vary depending on the method used to measure metabolism of an incubating bird. Therefore, we evaluated the energy expenditure of six male and four female wandering albatrosses (Diomedea exulans Linnaeus) using ...
Costa, D P, Shaffer, Scott A, Weimerskirch, H   +2 more
core   +1 more source