Results 51 to 60 of about 265,083 (248)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Association Between Fat Free Mass and Basal Metabolic Rate with Handgrip Strength in Female Medical Students

Jurnal Pendidikan Jasmani dan Olahraga
Handgrip strength is an indicator of general muscle strength. Low handgrip strength is associated with various diseases that can increase morbidity and mortality. Fat free mass and basal metabolic rate are indicators of health and physical fitness.
Noor Az Zhahra, Mila Citrawati, Sri Wahyuningsih, Maria Selvester Thadeus   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Estimating the agreement between the metabolic rate calculated from prediction equations and from a portable indirect calorimetry device: an effort to develop a new equation for predicting resting metabolic rate

Nutrition & Metabolism, 2018
Background Many studies have been performed over time in order to determine the reliability of metabolic rate prediction equations. Purpose To evaluate the agreement, in terms of bias, absolute bias and accuracy between metabolic rate prediction ...
Eleni Pavlidou, Dimitris Petridis, Maria Tolia, Nikolaos Tsoukalas, Antigoni Poultsidi, Aristeidis Fasoulas, George Kyrgias, Constantinos Giaginis   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Energic metabolism studies in pediatric cancer patients

Медицинский вестник Юга России, 2010
The aim. To estimate heat capacity (C) measurements for individual dietary support of pediatric cancer patients during chemotherapy. Material and methods. 43 cancer children are examined.
M. V. Konovalova, A. Yu. Vashura, D. V. Litvinov, E. V. Skorobogatova, N. E. Filippova, S. V. Belmer, G. Ya. Tseitlin   +6 more
doaj  

Coping with Salt Water Habitats: Metabolic and Oxidative Responses to Salt Intake in the Rufous-Collared Sparrow

Frontiers in Physiology, 2017
Many physiological adjustments occur in response to salt intake in several marine taxa, which manifest at different scales from changes in the concentration of individual molecules to physical traits of whole organisms.
Pablo Sabat, Pablo Sabat, Cristóbal Narváez, Isaac Peña-Villalobos, Carolina Contreras, Karin Maldonado, Juan C. Sanchez-Hernandez, Seth D. Newsome, Roberto Nespolo, Francisco Bozinovic, Francisco Bozinovic   +10 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

The Difference between the Basal Metabolic Rate and the Sleeping Metabolic Rate in Japanese

Journal of Nutritional Science and Vitaminology, 2004
Previous studies have demonstrated the difference between the basal metabolic rate (BMR) and the sleeping metabolic rate (SMR): however, the difference in the Japanese population has not yet been explored. This study examined the relationship between the BMR and SMR in ninety-four healthy Japanese subjects (37 males and 57 females, 39 +/- 12 y of age ...
Kumahara, H., Yoshioka, M., Yoshitake, Y., Shindo, M., Schutz, Y., Tanaka, H.   +5 more
openaire   +5 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source