Results 201 to 210 of about 348,538 (259)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Dietary baicalin supplementation enhances growth performance in fattening Hu sheep via dual modulation of immunity and gastrointestinal microbiome-metabolic crosstalk. [PDF]

J Anim Sci Biotechnol
Ding D, Zhang Y, Tian H, Dong B, Wu X, Liu S, Gao T, Zhang L, Fu T.   +8 more
europepmc   +1 more source

Dietary Chlorogenic Acid Attenuates Hepatic Lipid Accumulation and Reprograms Lipid Metabolism in Heat-Stressed Laying Hens: Integrated Transcriptomic and Metabolomic Analyses. [PDF]

Biology (Basel)
Wang D, Tan H, Peng L, Wu X, Gao J, Ma W.   +5 more
europepmc   +1 more source

Dual-action peptide KWH₂ protects against Salmonella choleraesuis diarrhea in weaned piglets by enhancing intestinal barrier integrity and modulating GSK-3β/Myc signaling. [PDF]

Vet Res
Zhu Y, Lv K, Tian Z, Han Y, Bi Z, Dong N.   +5 more
europepmc   +1 more source

Relationships Between Regional and Ectopic Adiposity and Insulin Sensitivity in Early and Late Pregnancy. [PDF]

Diabetes Care
Purnell JQ, Marshall N, Francisco M, Leo M, Rooney WD, Baetscher E, Frias A, Valent A, Catalano P, King J, Vesco KK.   +10 more
europepmc   +1 more source

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BASAL METABOLISM

Archives of Internal Medicine, 1928
The rise in metabolism due to work is well known. 1 Boothby and Sandiford 2 found that patients with exophthalmic goiter and adenomatous goiter with hyperthyroidism require nearly twice as much energy for a given piece of work as do normal persons or even patients with other diseases.
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