Results 231 to 240 of about 650,662 (345)

Energy intake for maintenance in a mammal with a low basal metabolism, the giant anteater (Myrmecophaga tridactyla)

, 2011
Marie Ståhl, Christine Osmann, Sylvia Ortmann, Michael Kreuzer, Jean‐Michel Hatt, Marcus Clauß   +5 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Dietary Guanidinoacetic Acid Supplementation Improves Growth Performance of Plateau Yaks Through Plasma Metabolome Modulation. [PDF]

Biology (Basel)
You Y, Zhang L, Fu L, Dong X, Peng Z, Zeng Y, Wang G, Chen J, Gao Y, Zhou J.   +9 more
europepmc   +1 more source

Rice JASMONIC ACID OXIDASES control resting jasmonate metabolism to promote growth and repress basal immune responses [PDF]

Simon Y. A. Ndecky, Ludivine Malherbe, Claire Villette, Véronique Chalvon, Isabelle Meusnier, Dennisse Beltran-Valencia, Nicolas Baumberger, Michael Riemann, Thomas Kroj, Antony Champion, Thierry Heitz   +10 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Effects of hydroxy methionine analog iron chelate on growth performance, blood parameters, and iron metabolism in weaned piglets. [PDF]

Sci Rep
Fu Y, Fang J, Ge Y, Zhang S, Liu Y, Zhou G, Yuan X, Jiao N, Li Y, Yang W.   +9 more
europepmc   +1 more source

Investigating the Impact of SN-38 on Mouse Brain Metabolism Based on Metabolomics

Xiaodong Zhu, Ya Huang, Jia Ding, Jianguo Liu, Changmeng Cui, Guangkui Han   +5 more
openalex   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Corrigendum to “Mortality in metabolic dysfunction-associated steatotic liver disease: A nationwide population-based cohort study” [Metabolism, Volume 152, March 2024, 155789] [PDF]

Eugene Han, Byung‐Wan Lee, Eun Seok Kang, Bong Soo, Sang Hoon Ahn, Yong‐ho Lee, Seung Up Kim   +6 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source