Results 41 to 50 of about 348,538 (259)

Active microbial ecosystem in glacier basal ice fuelled by iron and silicate comminution‐derived hydrogen

MicrobiologyOpen, 2021
The basal zone of glaciers is characterized by physicochemical properties that are distinct from firnified ice due to strong interactions with underlying substrate and bedrock.
Mario Toubes‐Rodrigo, Sanja Potgieter‐Vermaak, Robin Sen, Edda S. Oddsdóttir, David Elliott, Simon Cook   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Underestimation of resting metabolic rate using equations compared to indirect calorimetry in normal-weight subjects: Consideration of resting metabolic rate as a function of body composition

Clinical Nutrition Open Science, 2021
Summary: Background & aims: Resting metabolic rate (RMR) can either be estimated using specific equations or measured with indirect calorimetry (iCal). The calculation formulas usually exclude body composition.
Hannes Nösslinger, Ewald Mair, Hermann Toplak, Marlies Hörmann-Wallner   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Relation between Healthy Eating Index and Resting Metabolic Rate

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2020
Background and Objectives: Previouse studies demonstrated inverse association between healthy eating index and alot of chronic diseases like cardiovascular disease and cancer and mortality.
Mojdeh Ebaditabar, Samira Davarzani, Nadia Babaei, sakineh Shabbidar   +3 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Estimated Energy Requirement: Comparison Between the 2005 and 2023 Dietary Reference Intakes in Sedentary Adults and Older Adults—A Retrospective Cross-Sectional Study

Obesities
Background: Equations for estimating energy expenditure are developed for specific populations and contexts, including clinical settings, body composition variations, and age groups, to enhance precision in nutritional planning and health promotion ...
Anderson Matheus Oliveira Haas Verdi, Jaqueline Machado Soares, Jaqueline Fernandes Carneiro, Izadora Oliveira Felez, Dalton Luiz Schiessel, Daniele Gonçalves Vieira, Adriana Masiero Kühl, Daniela Caetano Gonçalves, Angelica Rocha de Freitas Melhem   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source