Results 51 to 60 of about 1,675,267 (255)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Effects of tuberculosis and HIV infection on whole-body protein metabolism during feeding, measured by the [15N]glycine method

, 2003
Background: Tuberculosis (TB) and HIV infection are wasting diseases that frequently occur together and have severe consequences on nutritional status.Objective: The objective was to determine the effects of TB and HIV, separately and together, on ...
Jackson, Alan A., Persaud, Chandarika, Ng, Yau-Ming, Paton, Nicholas I., Chee, Cynthia B.E.   +4 more
core   +2 more sources

The Role of Exercise – Rehabilitation on Energy Cost and Metabolic Efficiency in Dipelegic Spastic Cerebral Palsy Children

پزشکی بالینی ابن سینا, 2005
Introduction & Objective: The aim of this study was to compare the resting energy expenditure and metabolic efficiency before and after of aerobic exercise in spastic cerebral palsy children (mean age of 11 years) and also to compare with those of normal
Mojtaba Izadi, Farzad Nazem, Mohammad Mahdi Taghdiri, Farahpour   +3 more
doaj  

Underestimation of resting metabolic rate using equations compared to indirect calorimetry in normal-weight subjects: Consideration of resting metabolic rate as a function of body composition

Clinical Nutrition Open Science, 2021
Summary: Background & aims: Resting metabolic rate (RMR) can either be estimated using specific equations or measured with indirect calorimetry (iCal). The calculation formulas usually exclude body composition.
Hannes Nösslinger, Ewald Mair, Hermann Toplak, Marlies Hörmann-Wallner   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of temperature and glia in brain size enlargement and origin of allometric body-brain size scaling in vertebrates [PDF]

, 2014
Background: Brain signaling requires energy. The cost of maintaining and supporting energetically demanding neurons is the key constraint on brain size.
Feng, Jianfeng, Jianfeng Feng, Sachdev, Robert, Karbowski, Jan, Yu, Yuguo, Jan Karbowski, Yuguo Yu, Robert NS Sachdev   +7 more
core   +2 more sources

Active microbial ecosystem in glacier basal ice fuelled by iron and silicate comminution‐derived hydrogen

MicrobiologyOpen, 2021
The basal zone of glaciers is characterized by physicochemical properties that are distinct from firnified ice due to strong interactions with underlying substrate and bedrock.
Mario Toubes‐Rodrigo, Sanja Potgieter‐Vermaak, Robin Sen, Edda S. Oddsdóttir, David Elliott, Simon Cook   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

SEASONAL AND GEOPGRAPHICAL VARIATION IN DOWNY WOODPECKER (PICOIDES PUBESCENS) METABOLISM AND THERMOREGULATION [PDF]

, 2012
A Thesis Submitted In Partial Fulfillment of the Requirements For the Degree of Master of Science - BiologyDowny woodpeckers (Picoides pubescens) are small, non-migratory, nonpasserine birds.
Cousineau, Christopher J
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