Results 61 to 70 of about 1,675,267 (255)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms. [PDF]

, 2007
BACKGROUND: There is a wide variation in susceptibility to health effects of arsenic, which, in part, may be due to differences in arsenic metabolism.
Eugen Gurzau, Vahter, Marie, Gurzau, Eugen, Rajiv Kumar, Goessler, Walter, Ranjit Thirumaran, Leonardi, Giovanni, Kumar, Rajiv, Marie Vahter, Tony Fletcher, Anna-Lena Lindberg, Koppova, Kvetoslava, Giovanni Leonardi, Fletcher, Tony, Walter Goessler, Peter Rudnai, Kvetoslava Koppova, Rudnai, Peter, Thirumaran, Ranjit, Lindberg, Anna-Lena   +19 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Breast Cancer Subtypes Underlying EMT-Mediated Catabolic Metabolism

, 2020
Efficient catabolic metabolism of adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide phosphate (NADPH) is essentially required for cancer cell survival, especially in metastatic cancer progression.
Eunae Cho, Nam Kim, Hyun Kim, Sue Cho, Jun Yun, Jong Yook   +5 more
core   +1 more source

Agrin binds to the nerve-muscle basal lamina via laminin. [PDF]

, 1997
Agrin is a heparan sulfate proteoglycan that is required for the formation and maintenance of neuromuscular junctions. During development, agrin is secreted from motor neurons to trigger the local aggregation of acetylcholine receptors (AChRs) and other ...
Brandenberger, R, Ralph Brandenberger, Matthias Gesemann, Gesemann, M., Denzer, A. J., Chiquet, M, Ruegg, M. A., Denzer, A J, Brandenberger, R., Markus A. Ruegg, Matthias Chiquet, Gesemann, M, Ruegg, M A, Chiquet, M., Alain J. Denzer   +14 more
core   +1 more source

Relation between Healthy Eating Index and Resting Metabolic Rate

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2020
Background and Objectives: Previouse studies demonstrated inverse association between healthy eating index and alot of chronic diseases like cardiovascular disease and cancer and mortality.
Mojdeh Ebaditabar, Samira Davarzani, Nadia Babaei, sakineh Shabbidar   +3 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Astrocytes from P301S Tau mice exhibit non-canonical protein secretion and reduced morphological complexity

Neural Regeneration Research
Astrocytes have important neurosupportive functions in the brain that are altered in neurodegenerative diseases by unresolved mechanisms. We showed previously that astrocytes cultured from mice transgenic for human P301S-tau (P301S-mice) recapitulate the
Aishwarya G. Nadadhur, Matthew Mason, Johanna S. Rees, Marta Sidoryk-Wegrzynowicz, Aviva M. Tolkovsky, Maria Grazia Spillantini   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reduction in sucrose contents by downregulation of fructose-1,6-bisphosphatase 2 causes tiller outgrowth cessation in rice mutants lacking glutamine synthetase1;2

Rice, 2018
Background Our previous transcriptomic analysis revealed that downregulation of nitrogen and carbon metabolism in the basal portions of the shoots inhibited cytosolic glutamine synthetase1;2 (GS1;2), which severely reduced rice tiller number.
Miwa Ohashi, Keiki Ishiyama, Miyako Kusano, Atsushi Fukushima, Soichi Kojima, Toshihiko Hayakawa, Tomoyuki Yamaya   +6 more
doaj   +1 more source