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Case Report: Biallelic variants in <i>MRPS36</i>, encoding a component of the 2-oxoglutarate dehydrogenase complex, cause leigh syndrome. [PDF]

Front Pediatr
Jiang H, Xu C, Liu Z, Duan R, Yao X, Fu X, Xu J, Kang X, Yu T, Wang Y, Fang F.   +10 more
europepmc   +1 more source

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Cyclosporine A-enhanced cardioplegia preserves mitochondrial basal respiration after ischemic arrest

Perfusion, 2021
Background: Mitochondrial permeability transition pore (mPTP) opening plays a crucial role in cell death during ischemia-reperfusion injury (IRI). Cyclosporine A (CsA) inhibits mPTP opening. This study aimed to investigate the effects of CsA treatment during cardioplegia on the mitochondrial function and cardiac IRI.
Alexandro A Hoyer, Kristin Klaeske, Jack Garnham, Philipp Kiefer, Aida Salameh, Klaus Witte, Michael Borger, Maja-Theresa Dieterlen   +7 more
openaire   +2 more sources

Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts

Toxicology, 2015
Doxorubicin (DOX) is currently used in cancer chemotherapy, however, its use often results in adverse effects highlighted by the development of cardiomyopathy and ultimately heart failure. Interestingly, DOX cardiotoxicity is decreased by resveratrol or by physical activity, suggesting that increased mitochondrial activity may be protective. Conversely,
Cláudia M, Deus, Cheryl, Zehowski, Kendra, Nordgren, Kendall B, Wallace, Andrew, Skildum, Paulo J, Oliveira   +5 more
openaire   +2 more sources

Is soil basal respiration a good indicator of soil pollution?

Geoderma, 2016
Abstract Metal(loid)s are common pollutants in soils, causing a significant toxicological risk to living organisms and to the ecosystems. Soil basal respiration (SBR) is broadly used as indicator of metal(loid) stress in polluted soils, although the correlation with toxicity gives in many cases contradictory results.
A. Romero-Freire, M. Sierra Aragón, F.J. Martínez Garzón, F.J. Martín Peinado   +3 more
openaire   +1 more source

Basal metabolism and respiration in men living at 5,800 m (19,000 ft)

Journal of Applied Physiology, 1964
Respiratory determinations were carried out on eight members of the Himalayan Scientific and Mountaineering Expedition 1960—1961 and three Sherpas during a prolonged stay at 5,800 m (19,000 ft). Ventilation and oxygen uptake were similar in both groups, although the Sherpas were smaller men.
M B, GILL, L G, PUGH
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Pyruvate carboxylase supports basal ATP-linked respiration in human pluripotent stem cell-derived brown adipocytes

Biochemical and Biophysical Research Communications, 2021
Brown adipocytes (BA) are a specialized fat cell which possesses a high capacity for fuel oxidation combined with heat production. The maintenance of high metabolic activity in BA requires elevated oxidation of fuel through the tricarboxylic acid cycle.
Udom Lao-On, Timothy S. Cliff, Stephen Dalton, Sarawut Jitrapakdee   +3 more
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Genomic and Phenomic Correlations in the Respiration of Basal Cell Carcinomas

2003
Early last century Warburg1 described differences in metabolism between normal and cancer cells, however subsequent research did not bear out what he considered to be the “primary cause of cancer,” i.e., the replacement of respiration by fermentation 2.
Maguire, David, Lintell, Nicholas, McCabe, Michael, Griffiths, Lyn, Ashton, Kevin   +4 more
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Basal and maintenance respiration of mycorrhizal and nonmycorrhizal root systems of conifers

Canadian Journal of Forest Research, 1987
We measured CO2 efflux from root systems of mycorrhizal and nonmycorrhizal conifer seedlings planted in silica sand and maintained in darkness for 11 to 15 days. We first compared methods of isolating the root system for root respiration measurement using Douglas-fir seedlings (Pseudotsugamenziesii (Mirb.) Franco).
John D. Marshall, David A. Perry
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Ecotoxicity of parathion during its dissipation mirrored by soil enzyme activity, microbial biomass and basal respiration

Chemosphere, 2023
The application of parathion (PTH) in agriculture can result in its entry into the soil and threaten the soil environment. Monitoring the PTH residues and assessing toxicity on soil health are of paramount importance to the public. Herein, the dissipation of PTH and concomitant influence on microbial activities [FDA hydrolase (FDA‒H), microbial biomass
Tao, Kelin, Tian, Haixia, Wang, Ziquan, Shang, Xiaofu, Fan, Jing, Megharaj, Mallavarapu, Ma, Jianli, Jia, Hanzhong, He, Wenxiang   +8 more
openaire   +2 more sources