Results 1 to 10 of about 119,150 (162)

Menstrual cycle influence on skeletal muscle mitochondrial respiration in humans [PDF]

Physiological Reports
The menstrual cycle influences function in various tissues in the body. We sought to determine if menstrual cycle phase could influence mitochondrial function in skeletal muscle in females.
W. Bradley Nelson, Brandon S. Pfeifer, Ashley R. Lovell, Erik D. Marchant, Briell V. Mitchell, Erin L. Atkinson, Trevor L. Murphy, Sydney L. Poulsen, Jay R. K. Baird, Chad R. Hancock, Robert D. Hyldahl   +10 more
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A novel extracellular flux assay workflow uncovers impaired sciatic nerve mitochondrial respiration in diabetic db/db mice [PDF]

Cell Communication and Signaling
Abnormal mitochondrial function contributes to the development of diabetic neuropathy by inducing oxidative stress and altering energy metabolism, ultimately leading to neuronal damage.
Sebastian Sill, D. Margriet Ouwens, Fariba Zivehe, Sonja Hartwig, Stefan Lehr, Gidon J. Bönhof, Michael Roden, Hadi Al-Hasani, Alexandra Chadt, Alexander Strom   +9 more
doaj   +2 more sources

Control of mitochondrial respiration [PDF]

FEBS Letters, 1983
The control theory of Kacser and Burns [in: Rate Control of Biological Processes (Davies, D.D. ed) pp. 65–104, Cambridge University Press, London, 1973] and Heinrich and Rapoport ([Eur. J. Biochem. (1974) 42, 97‐105] has been used to quantify the amount of control exerted by different steps on mitochondrial oxidative phosphorylation in rat‐liver ...
Tager, J.M., Wanders, R.J.A, Groen, A.K., Kunz, W., Bohnensack, R., Küster, U., Letko, G., Böhme, G., Duszynski, J., Wojtczak, L.   +9 more
  +8 more sources

Analysis of oxygen consumption rates in zebrafish reveals differences based on sex, age and physical activity recovery

Frontiers in Physiology, 2023
Introduction: Mitochondrial dysfunction is linked to a variety of human diseases. Understanding the dynamic alterations in mitochondrial respiration at various stages of development is important to our understanding of disease progression.
Bridget Konadu, Jonathan P. Hosler, Yann Gibert, Kristin S. Edwards, Kristin S. Edwards   +4 more
doaj   +1 more source

Age-Dependent Alterations in Platelet Mitochondrial Respiration

Biomedicines, 2023
Mitochondrial dysfunction is an important cellular hallmark of aging and neurodegeneration. Platelets are a useful model to study the systemic manifestations of mitochondrial dysfunction.
Zdeněk Fišar, Jana Hroudová, Martina Zvěřová, Roman Jirák, Jiří Raboch, Eva Kitzlerová   +5 more
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How to Measure Mitochondrial Oxygen Respiration [PDF]

운동과학, 2023
PURPOSE With the widespread of mitochondrial function, the need to accurately quantify and comprehend mitochondrial O2 respiration has gained prominence within the physiological and pathological spheres.
Jun-Won Heo, Eun-Jeong Cho, Youngju Choi, Dae Yun Seo, Jin Han, Dong-Ho Park, Ju-Hee Kang, Hyo-Bum Kwak   +7 more
doaj   +1 more source

FKBP4 regulates 5-fluorouracil sensitivity in colon cancer by controlling mitochondrial respiration

Life Science Alliance, 2022
FKBP4 controls mitochondrial respiration via modulating COA6-mediated biogenesis and activity of mitochondrial complex IV, thereby regulating 5-fluorouracil sensitivity in colon cancer.
Zhenyu Zhu, Qingsheng Hou, Bishi Wang, Changhao Li, Luguang Liu, Weipeng Gong, Jie Chai, Hongliang Guo, Yanhan Jia   +8 more
doaj   +1 more source

Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function. [PDF]

PLoS ONE, 2014
The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis ...
Fredrik Sjövall, Saori Morota, Eleonor Åsander Frostner, Magnus J Hansson, Eskil Elmér   +4 more
doaj   +3 more sources

A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise

Scientific Reports, 2023
A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes mitochondrial respiration and attenuates mitochondrial oxidative stress in cultured cardiomyocytes.
Kirsten T. Nijholt, Pablo I. Sánchez-Aguilera, Belend Mahmoud, Albert Gerding, Justina C. Wolters, Anouk H. G. Wolters, Ben N. G. Giepmans, Herman H. W. Silljé, Rudolf A. de Boer, Barbara M. Bakker, B. Daan Westenbrink   +10 more
doaj   +1 more source

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

Molecular Metabolism, 2022
Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer, Jessica Huang, Arrienne Butic, Caroline Perry, Tal Yardeni, Wendy Tan, Ryan Morrow, Joseph A. Baur, Douglas C. Wallace   +8 more
doaj   +1 more source