Results 1 to 10 of about 491,817 (253)
Age-Dependent Alterations in Platelet Mitochondrial Respiration
Biomedicines, 2023 Mitochondrial dysfunction is an important cellular hallmark of aging and neurodegeneration. Platelets are a useful model to study the systemic manifestations of mitochondrial dysfunction.
Zdeněk Fišar +5 more
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Analysis of mitochondrial respiration and ATP synthase in frozen brain tissues
Heliyon, 2023 Studying mitochondrial respiration capacity is essential for gaining insights into mitochondrial functions. In frozen tissue samples, however, our ability to study mitochondrial respiration is restricted by damage elicited to the inner mitochondrial ...
Myriam Gorospe +2 more
exaly +3 more sources
Control of mitochondrial respiration [PDF]
FEBS Letters, 1983 The control theory of Kacser and Burns [in: Rate Control of Biological Processes (Davies, D.D. ed) pp. 65–104, Cambridge University Press, London, 1973] and Heinrich and Rapoport ([Eur. J. Biochem. (1974) 42, 97‐105] has been used to quantify the amount of control exerted by different steps on mitochondrial oxidative phosphorylation in rat‐liver ...
Tager, J.M. +9 more
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Frontiers in Physiology, 2023 Introduction: Mitochondrial dysfunction is linked to a variety of human diseases. Understanding the dynamic alterations in mitochondrial respiration at various stages of development is important to our understanding of disease progression.
Bridget Konadu +4 more
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How to Measure Mitochondrial Oxygen Respiration [PDF]
운동과학, 2023 PURPOSE With the widespread of mitochondrial function, the need to accurately quantify and comprehend mitochondrial O2 respiration has gained prominence within the physiological and pathological spheres.
Jun-Won Heo +7 more
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FKBP4 regulates 5-fluorouracil sensitivity in colon cancer by controlling mitochondrial respiration
Life Science Alliance, 2022 FKBP4 controls mitochondrial respiration via modulating COA6-mediated biogenesis and activity of mitochondrial complex IV, thereby regulating 5-fluorouracil sensitivity in colon cancer.
Zhenyu Zhu +8 more
doaj +1 more source
Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function. [PDF]
PLoS ONE, 2014 The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis ...
Fredrik Sjövall +4 more
doaj +3 more sources
Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice
Molecular Metabolism, 2022 Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer +8 more
doaj +1 more source
Scientific Reports, 2023 A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes mitochondrial respiration and attenuates mitochondrial oxidative stress in cultured cardiomyocytes.
Kirsten T. Nijholt +10 more
doaj +1 more source
Invasive and noninvasive markers of human skeletal muscle mitochondrial function
Physiological Reports, 2023 Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess skeletal muscle mitochondrial capacity, we tested how well different invasive and noninvasive markers ...
Rodrigo Mancilla +10 more
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