Results 21 to 30 of about 645,590 (301)

Modulation of Human Sperm Mitochondrial Respiration Efficiency by Plant Polyphenols

Antioxidants, 2021
Plant bioactives, such as polyphenols, can differentially affect (positively or negatively) sperm quality, depending on their concentration. These molecules have been proposed as natural scavengers of reactive oxygen species (ROS) for male infertility ...
Alessandra Ferramosca, Stefano Lorenzetti, Mariangela Di Giacomo, Paola Lunetti, Francesco Murrieri, Loredana Capobianco, Vincenza Dolce, Lamberto Coppola, Vincenzo Zara   +8 more
doaj   +1 more source

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α : modulation by p38 MAPK [PDF]

, 2004
The transcriptional coactivator PPAR gamma coactivator 1 α (PGC-1α) is a key regulator of metabolic processes such as mitochondrial biogenesis and respiration in muscle and gluconeogenesis in liver. Reduced levels of PGC-1α in humans have been associated
Lin, J., Jaeger, S., Tempst, P., Puigserver, P., Fan, M., Handschin, C., St-Pierre, J., Spiegelman, B. M., Rhee, J., Erdjument-Bromage, H.   +9 more
core   +1 more source

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival [PDF]

, 2011
Hypoxia is one of the features of poorly vascularised areas of solid tumours but cancer cells can survive in these areas despite the low oxygen tension.
Tennant, D.A., Zheng, L, Appanna, VD, Watson David G., Kalna, G., Hedley Barbara A., Papkovsky, Dmitri B, Gottlieb Eyal, Papkovsky, D.B., Christian Frezza, Dmitri B. Papkovsky, Frezza, Christian, Hedley, Barbara A, Zheng Liang, Liang Zheng, Hedley, BA, Watson, DG, Kalna, Gabriela, Dmitri B Papkovsky, Tennant, Daniel A., Gabriela Kalna, Frezza, C, Watson, David, Eyal Gottlieb, Tennant Daniel A., Gottlieb, Eyal, Gottlieb, E., David G. Watson, Frezza Christian, Kalna Gabriela, Hedley, B., Daniel A Tennant, Frezza, C., Kalna, G, Barbara A. Hedley, Zheng, L., Barbara A Hedley, Tennant, Daniel; id_orcid, Gottlieb, E, David G Watson, Papkovsky, DB, Papkovsky Dmitri B., Zheng, Liang, Watson, D.G., Daniel A. Tennant   +44 more
core   +4 more sources

Assessment of mitochondrial respiratory capacity using minimally invasive and noninvasive techniques in persons with spinal cord injury.

PLoS ONE, 2022
PurposeMuscle biopsies are the gold standard to assess mitochondrial respiration; however, biopsies are not always a feasible approach in persons with spinal cord injury (SCI).
Raymond E Lai, Matthew E Holman, Qun Chen, Jeannie Rivers, Edward J Lesnefsky, Ashraf S Gorgey   +5 more
doaj   +2 more sources

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart [PDF]

, 2014
Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart.
Fernandez, BO, Andrew S. Cowburn, Ashmore, T., Johnson, RS, Cristina Branco‐Price, James A. West, Heather, LC, Fernandez, Bernadette O, Cowburn, Andrew S, Feelisch, Martin, Ashmore, T, Martin Feelisch, Branco-Price, Cristina, Andrew J. Murray, Heather, Lisa C, Branco-Price, C, Griffin, Julian L, Cowburn, A. S., Heather, L. C., Griffin, J. L., Murray, Andrew J, Feelisch, M., Julian L. Griffin, West, J. A., Johnson, R. S., West, JA, Lisa C. Heather, Feelisch, M, Johnson, Randall S, West, James A, Griffin, JL, Murray, AJ, Fernandez, B. O., Branco-Price, C., Tom Ashmore, Cowburn, AS, Bernadette O. Fernandez, Murray, A. J., Ashmore, Tom, Randall S. Johnson   +39 more
core   +2 more sources

The emerging role of Nrf2 in mitochondrial function [PDF]

, 2015
The transcription factor NF-E2 p45-related factor 2 (Nrf2, gene name NFE2L2) allows adaptation and survival under conditions of stress by regulating the gene expression of diverse networks of cytoprotective proteins, including antioxidant, anti ...
Dinkova-Kostova, AT, Abramov, Andrey Y., Dinkova-Kostova, Albena T.; id_orcid, Abramov, AY   +3 more
core   +1 more source

Supplementary Table 2 Mitochondrial Respiration-.docx

, 2020
Data are displayed as mean +/- SEM. Mitochondrial specific (Mito-specific) values were calculated by normalising mass-specific mitochondrial respiration values to CS activity (values expressed per kilogram of protein).
Mary Woessner (8068229)
core   +1 more source

Effects of endotoxin and catecholamines on hepatic mitochondrial respiration [PDF]

, 2009
Catecholamines are frequently used in sepsis, but their interaction with mitochondrial function is controversial. We incubated isolated native and endotoxin-exposed swine liver mitochondria with either dopamine, dobutamine, noradrenaline or placebo for 1
Hiltebrand, Luzius B, Bracht, Hendrik, Weikert, Christian, Brandt, Sebastian, Beck, Mario, Jakob, Stephan M, Porta, Francesca, Takala, Jukka, Jakob SM, Beck M, Brandt S, Bracht H, Weikert C, Takala J, Porta F, Hiltebrand LB   +15 more
core   +2 more sources

Superior Intrinsic Mitochondrial Respiration in Women Than in Men

Frontiers in Physiology, 2018
Sexual dimorphism is apparent in humans, however, to date no studies have investigated mitochondrial function focusing on intrinsic mitochondrial respiration (i.e., mitochondrial respiration for a given amount of mitochondrial protein) and mitochondrial ...
Daniele A. Cardinale, Filip J. Larsen, Tomas A. Schiffer, David Morales-Alamo, David Morales-Alamo, Björn Ekblom, Jose A. L. Calbet, Jose A. L. Calbet, Jose A. L. Calbet, Hans-Christer Holmberg, Hans-Christer Holmberg, Robert Boushel   +11 more
doaj   +1 more source

Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice

Nature Communications, 2023
Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is activated in BAT during cold stress and dissipates mitochondrial proton motive ...
Anna Park, Kwang-eun Kim, Isaac Park, Sang Heon Lee, Kun-Young Park, Minkyo Jung, Xiaoxu Li, Maroun Bou Sleiman, Su Jeong Lee, Dae-Soo Kim, Jaehoon Kim, Dae-Sik Lim, Eui-Jeon Woo, Eun Woo Lee, Baek Soo Han, Kyoung-Jin Oh, Sang Chul Lee, Johan Auwerx, Ji Young Mun, Hyun-Woo Rhee, Won Kon Kim, Kwang-Hee Bae, Jae Myoung Suh   +22 more
doaj   +1 more source