Results 91 to 100 of about 2,385,323 (336)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Nest climate and blood quality of two host species of the ectoparasitic Philornis downsi in the Galapagos Islands as factors of larval development

Frontiers in Ecology and Evolution
The avian vampire fly is an invasive species on the Galapagos Islands, where its hematophagous larvae utilize nestling birds as hosts. It poses a serious threat to populations and species of Darwin finches and other avian species.
Courtney L. Pike, Rebecca Hood-Nowotny, Barbara Kofler, Heinz Richner, Sabine Tebbich   +4 more
doaj   +1 more source

Genome-wide nucleotide patterns and potential mechanisms of genome divergence following domestication in maize and soybean

Genome Biology, 2019
Background Plant domestication provides a unique model to study genome evolution. Many studies have been conducted to examine genes, genetic diversity, genome structure, and epigenome changes associated with domestication.
Jinyu Wang, Xianran Li, Kyung Do Kim, Michael J. Scanlon, Scott A. Jackson, Nathan M. Springer, Jianming Yu   +6 more
doaj   +1 more source

Quality assurance procedures for V378A matrix resin [PDF]

, 1985
A characterization methodology has been developed on which to base quality assurance procedures for U.S. Polymeric V378A bismaleimide matrix resin. Chemical composition is established by partition reverse phase and size exclusion liquid chromatography ...
Dynes, P. J., Hamermesh, C. L.
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Development of the Tablet Dosage Form Composition for the Inductor of Hepatocytes Monooxygenase System Based on 6,8-dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-F]xanthine

, 2023
AV Petrakov, Vladimir V. Sheikin, С. В. Кривощеков, Ekaterina Bezverkhniaia, A. M. Guryev, М. В. Белоусов   +5 more
openalex   +2 more sources

The Effect of Composition on Nova Ignitions

, 2008
The accretion of hydrogen-rich matter onto C/O and O/Ne white dwarfs in binary systems leads to unstable thermonuclear ignition of the accreted envelope, triggering a convective thermonuclear runaway and a subsequent classical, recurrent, or symbiotic ...
Alexakis, Balser, Balser, Cassisi, Fujimoto, Glasner, Glasner, Gänsicke, Hachisu, Hachisu, Howell, José, José, José, José, José, Ken J. Shen, Kercek, Kercek, Kippenhahn, Lars Bildsten, Lodders, Neill, Neill, Nomoto, Piersanti, Piro, Rogers, Rosner, Schatzmann, Shafter, Shen, Sienkiewicz, Sienkiewicz, Starrfield, Starrfield, Timmes, Timmes, Townsley, Townsley, Townsley, Truran, Warner, Williams, Winters, Woosley, Yaron   +46 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The study of structural-mechanical characteristics of the ointment with aminexil

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
The estimation of rheological characteristics is an important and essential fragment of investigations for creating semisolid dosage forms for dermatologic practice.
Zhamaly Karym, V. V. Hladyshev, A. P. Lysianska   +2 more
doaj   +1 more source

Microservice compositions based on the choreography of BPMN fragments: facing evolution issues [PDF]

, 2022
Jesús Ortiz, Victoria Torres, Pedro Valderas   +2 more
openalex   +1 more source