Results 101 to 110 of about 2,389,212 (289)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The development of cream-mask base composition for androgenetic alopecia prevention and treatment

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
Aim. Androgenetic Alopecia (AA) treatment nowadays is still a difficult task of dermatology as the range of drugs that affect the pathological link of disease and are safe for prolonged use, is limited. Methods and results. The purpose of the work was
M. I. Fedorovska
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The study of structural-mechanical characteristics of the ointment with aminexil

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
The estimation of rheological characteristics is an important and essential fragment of investigations for creating semisolid dosage forms for dermatologic practice.
Zhamaly Karym   +2 more
doaj   +1 more source

Corrosion resistance of sodium sulfate coated cobalt-chromium-aluminum alloys at 900 C, 1000 C, and 1100 C [PDF]

open access: yes
The corrosion of sodium sulfate coated cobalt alloys was measured and the results compared to the cyclic oxidation of alloys with the same composition, and to the hot corrosion of compositionally equivalent nickel-base alloys.
Santoro, G. J.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A method for automatic gamelan music composition

open access: yesIJAIN (International Journal of Advances in Intelligent Informatics), 2016
Aim of this study is designing a method for automatic gamelan music composition using rule-base expert system approach. The program is designed for non-expert user in order to help them composing gamelan music or analyzing their composition to achieve ...
Khafiizh Hastuti, Khabib Mustafa
doaj   +1 more source

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