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Quality-Based Recommendations for Mashup Composition [PDF]
, 2010 When composing mashups, the selection of suitable services is mainly based on functional requirements and does not consider the quality of the single services. In this paper, we show that the quality of component services can drive the production of recommendations that can help building quality mashups.
PICOZZI, MATTEO +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A method for automatic gamelan music composition
IJAIN (International Journal of Advances in Intelligent Informatics), 2016 Aim of this study is designing a method for automatic gamelan music composition using rule-base expert system approach. The program is designed for non-expert user in order to help them composing gamelan music or analyzing their composition to achieve ...
Khafiizh Hastuti, Khabib Mustafa
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Domain ontology knowledge base and its application in nursing practical domain
Huli yanjiu, 2017 It introduced the concept，composition and construction method of ontology knowledge base,and its application in the field of nursing practice at home and abroad.combined with China’s nursing information foundation，the feasibility of nursing practice to ...
ZHENG Jie
doaj
Purifying selection against spurious splicing signals contributes to the base composition evolution of the polypyrimidine tract. [PDF]
J Evol Biol, 2023 Yıldırım B, Vogl C.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Inverted base composition skews and discontinuous mitochondrial genome architecture evolution in the Enoplea (Nematoda). [PDF]
BMC Genomics, 2022 Zou H +7 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source