Base Composition Characteristics of Mammalian miRNAs [PDF]
Journal of Nucleic Acids, 2013 MicroRNAs (miRNAs) are short RNA sequences that repress protein synthesis by either inhibiting the translation of messenger RNA (mRNA) or increasing mRNA degradation.
Bin Wang
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Base Composition and Host Adaptation of the SARS-CoV-2: Insight From the Codon Usage Perspective [PDF]
Frontiers in Microbiology, 2021 The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading rapidly all over the world and has raised grave concern globally.
Ayan Roy +13 more
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Base composition, adaptation, and evolution of goose astroviruses: codon-based investigation [PDF]
Poultry Science, 2023 : Goose astroviruses (GoAstVs) are causative agents that account for fatal infection of goslings characterized by visceral urate deposition, resulting in severe economic losses in major goose-producing regions in China since 2017.
Fucheng Guo +4 more
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Variation in base composition underlies functional and evolutionary divergence in non-LTR retrotransposons [PDF]
Mobile DNA, 2020 Background Non-LTR retrotransposons often exhibit base composition that is markedly different from the nucleotide content of their host’s gene. For instance, the mammalian L1 element is AT-rich with a strong A bias on the positive strand, which results ...
Robert P. Ruggiero, Stéphane Boissinot
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Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition [PDF]
Frontiers in Microbiology, 2017 Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
Erica V. De Castro Levatti +7 more
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Local genic base composition impacts protein production and cellular fitness [PDF]
PeerJ, 2018 The maintenance of a G + C content that is higher than the mutational input to a genome provides support for the view that selection serves to increase G + C contents in bacteria.
Erik M. Quandt +2 more
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Evolution of Genomic Base Composition: From Single Cell Microbes to Multicellular Animals [PDF]
Computational and Structural Biotechnology Journal, 2019 Whole genome sequencing (WGS) of thousands of microbial genomes has provided considerable insight into evolutionary mechanisms in the microbial world.
Jon Bohlin, John H.-O. Pettersson
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Population genomic analysis of base composition evolution in Drosophila melanogaster. [PDF]
Genome Biology and Evolution, 2012 The relative importance of mutation, selection, and biased gene conversion to patterns of base composition variation in Drosophila melanogaster, and to a lesser extent, D. simulans, has been investigated for many years.
Begun, David J +4 more
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A predictable conserved DNA base composition signature defines human core DNA replication origins [PDF]
Nature Communications, 2020 In metazoan the DNA sequence elements characterizing origin specification are unknown. By generating and analysing 19 SNS-seq datasets from different human cell types, the authors reveal a class and features of Core origins of replication which can be ...
Ildem Akerman +15 more
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Compression rates of microbial genomes are associated with genome size and base composition [PDF]
Genomics & InformaticsBackground To what degree a string of symbols can be compressed reveals important details about its complexity. For instance, strings that are not compressible are random and carry a low information potential while the opposite is true for highly ...
Jon Bohlin, John H.-O. Pettersson
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