Results 201 to 210 of about 486,575 (254)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Mass spectrometric base composition profiling: Implications for forensic mtDNA databasing.

open access: yesForensic Sci Int Genet, 2013
Eduardoff M   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Impact of helicopter emergency medical services base operating regime (24 h vs. 07:00-20:00) on mission volume and structure in Poland: a cross-sectional-longitudinal analysis with duty-time standardization (10 March-10 August 2025). [PDF]

open access: yesBMC Health Serv Res
Żuratyński P   +13 more
europepmc   +1 more source

High Molecular Weight Chitosan from Shrimp Shells: Synthesis of <i>Para</i>-Substituted Schiff Bases with Selective Leishmanicidal Activity and Application in CO<sub>2</sub>/O<sub>2</sub>-Selective Films. [PDF]

open access: yesPolymers (Basel)
Yánez-Crespo AA   +9 more
europepmc   +1 more source

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