Results 221 to 230 of about 2,389,212 (289)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Intrinsic Hydrogen-Deuterium Exchange Rates in H₂O/D₂O Mixtures. [PDF]

J Phys Chem B
Grimaldi A, Stofella M, Paci E.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Patch type nucleotide sequence identities between genomes from many different species facilitate illegitimate recombination. [PDF]

Sci Rep
Weber S, Ramirez CM, Doerfler W.
europepmc   +1 more source

Nanoparticle-based Composites

Journal of the Japan Society of Colour Material, 2004
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Chemical signatures and sensory perception of <i>Nongxiangxing Baijiu</i>: regional and quality-grade discrimination and the modulatory role of ethanol. [PDF]

Food Chem X
Zhou R, Xiangli R, Zhao D, Zheng J, Su J, Feng Z, Ma Y, Xu Y.   +7 more
europepmc   +1 more source

Proximate composition and sensory evaluation of gluten-free bar formulated from rice and soybean flour. [PDF]

PeerJ
El-Deyarbi M, Abughoush M, Hegazy S, Aljaoune A, Aldeyarbi S, Aljuboori H, Alnuaimi H, Almatrooshi A, Adi ZS, Hussein AA, Nafea AE, Choudhury IH.   +11 more
europepmc   +1 more source

Steel based composites

Metal Powder Report, 2001
openaire   +1 more source