Results 41 to 50 of about 1,511,123 (311)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
, 2013 An experimental study has been conducted to validate theoretical solutions for the response of a base excited single degree-of-freedom isolation system possessing pure cubic damping.
Ferguson, N.S. +2 more
core
Glider: A GPU Library Driver for Improved System Security [PDF]
, 2014 Legacy device drivers implement both device resource management and isolation. This results in a large code base with a wide high-level interface making the driver vulnerable to security attacks.
Sani, Ardalan Amiri +2 more
core
Seismic analysis of base isolated buildings [PDF]
Archives of Computational Methods in Engineering, 1997 This paper presents a survey of the numerical simulation of base isolation systems for the vibration control of buildings and their equipment, primarilly against earthquakes. Base isolation has received much attention in the recent twenty years and many buildings have been protected using this technology.
Barbat, Alex, Bozzo, L.
openaire +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Base isolator with variable stiffness and damping: design, experimental testing and modelling [PDF]
, 2014 Vulnerability in base isolation system of civil structures originated from passive nature of the rubber material raises the urgency of developing smart base isolation system with adaptive and controllable properties, i.e.
Li, J, Li, Y
core
Frequency control of smart base isolation system employing a novel adaptive magneto-rheological elastomer base isolator [PDF]
, 2015 © The Author(s) 2015. In the past decades, base isolation techniques have become increasingly popular for seismic protection of civil structures owing to its capability of decoupling buildings from harmful ground motion.
Askari, M, Gu, X, Li, J, Li, Y
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
A broadband microwave Corbino spectrometer at $^3$He temperatures and high magnetic fields [PDF]
, 2014 We present the technical details of a broadband microwave spectrometer for measuring the complex conductance of thin films covering the range from 50 MHz up to 16 GHz in the temperature range 300 mK to 6 K and at applied magnetic fields up to 8 Tesla. We
Armitage, N. P., Liu, Wei, Pan, LiDong
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source