Results 51 to 60 of about 434,138 (268)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Comparative Analysis on Seismic Base Isolation for Integrated Fast Reactor Nuclear Power Plant
Yuanzineng kexue jishuThe fast reactor is one of the principal reactor types in the fourth generation of nuclear power technologies worldwide. The integrated closed-cycle fast reactor nuclear energy system (referred to as the integrated fast reactor) is a nuclear energy ...
MIAO Xin, ZHANG Botao, LIU Yizhe, LIU Linding
doaj +1 more source
Buildings, 2020 Base (seismic) isolation is a promising technology for seismic protection of buildings and other constructions. Nowadays, it is accepted that such a technique is efficient and reliable; however, it has two major limitations: soft foundation soil, and ...
Francisco López Almansa +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Analytical Behavior of Multi-Storied Building with Base Isolation Subjected to Earthquake Loading
Journal of Engineering and Sustainable Development, 2013 This study involves analysis of multi-storied building to explain the behavior under seismic earthquake loading in two cases, (i.e. with or without base isolation system).
Hadi Nasir Ghadhban AL-Maliki
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CivilEngBase isolation is known as a useful and popular technique for seismic upgrading of reinforced concrete buildings. Predicting damage levels based on relative inter-story drift plays an important role for designing optimal base isolation systems.
Mohamed Algamati +2 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
COMPARATIVE STUDY REGARDING THE NON-ISOLATED CIRCULAR ABOVE-GROUND PARKING LOT AND THE PARKING LOT ISOLATED BY MEANS OF THE BASE ISOLATION METHOD [PDF]
Journal of Research and Innovation for Sustainable Society, 2020 This paper studies the beneficial effects of the base isolation method. "The design/consolidation method by base isolation" consists in increasing the fundamental vibration period, decreasing displacement.
Edward RĂȘCHITOR +3 more
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Frontiers in Built Environment, 2020 This paper analyses the new Research Centre designed for the University of Camerino and entirely financed by the national Civil Protection Department (DPC), following the seismic events in Central Italy in 2016.
Andrea Dall’Asta +4 more
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