Results 1 to 10 of about 1,688,413 (180)
Frequency and Isostericity of RNA Base Pairs [PDF]
Nucleic Acids Research, 2009 Most of the hairpin, internal and junction loops that appear single-stranded in standard RNA secondary structures form recurrent 3D motifs, where non-WatsonCrick base pairs play a central role.
Stombaugh, Jesse +2 more
core +12 more sources
Highly specific unnatural base pair systems as a third base pair for PCR amplification [PDF]
Nucleic Acids Research, 2012 Toward the expansion of the genetic alphabet of DNA, we present highly efficient unnatural base pair systems as an artificial third base pair for PCR. Hydrophobic unnatural base pair systems between 7-(2-thienyl)imidazo[4,5-b]pyridine (Ds) and 2-nitro-4 ...
Akira Sato +42 more
core +7 more sources
The base-pairing ability of the base pair-mimic nucleosides [PDF]
Nucleic Acids Symposium Series, 2007 The deoxyadenosine derivative tethering the phenyl group at N6 of deoxyadenosine (A(phe)) was previously found to have a property to stack strongly with adjacent nucleotide bases in a DNA duplex. On the other hand, it was also demonstrated that DNA polymerases selectively incorporated dTTP opposite A(phe) in a template DNA strand.
Shu-ichi Nakano +3 more
openaire +3 more sources
The RNA Base-Pairing Problem and Base-Pairing Solutions [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 RNA molecules are folded into structures and complexes to perform a wide variety of functions. Determination of RNA structures and their interactions is a fundamental problem in RNA biology. Most RNA molecules in living cells are large and dynamic, posing unique challenges to structure analysis.
Zhipeng Lu, Howard Y. Chang
openaire +2 more sources
High Base Pair Opening Rates in Tracts of GC Base Pairs [PDF]
Journal of Biological Chemistry, 1999 Sequence-dependent structural features of the DNA double helix have a strong influence on the base pair opening dynamics. Here we report a detailed study of the kinetics of base pair breathing in tracts of GC base pairs in DNA duplexes derived from 1H NMR measurements of the imino proton exchange rates upon titration with the exchange catalyst ammonia.
Hartmut Fritzsche +2 more
openaire +3 more sources
The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair [PDF]
Organic & Biomolecular Chemistry, 2017 The 5-Cl-dU:7-deaza-dA base pair can be a substitute for the dT:dA base pair in an enzymatic replication process of 2 kb DNA.
Mikhail Abramov +4 more
openaire +5 more sources
DNA-Mediated Electrochemistry [PDF]
, 2008 The base pair stack of DNA has been demonstrated as a medium for long-range charge transport chemistry both in solution and at DNA-modified surfaces. This chemistry is exquisitely sensitive to structural perturbations in the base pair stack as occur with
Barton, Jacqueline K. +2 more
core +2 more sources
Schiff base-mediated base pairing [PDF]
Nucleic Acids Symposium Series, 2005 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chikara Dohno +2 more
openaire +4 more sources
Base Pairs to Populations [PDF]
Clinical Cancer Research, 2017 “There is much work to be done and many challenges exist in our mission to end the suffering that breast cancer brings.” So conclude Guest Editors Ann Partridge and Lisa Carey in their overview for this CCR Focus on breast cancer.
openaire +3 more sources
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources