Results 31 to 40 of about 1,859,090 (336)
DNA-Mediated Electrochemistry [PDF]
The base pair stack of DNA has been demonstrated as a medium for long-range charge transport chemistry both in solution and at DNA-modified surfaces. This chemistry is exquisitely sensitive to structural perturbations in the base pair stack as occur with
Barton, Jacqueline K. +2 more
core +2 more sources
Calculation of the Stabilization Energies of Oxidatively Damaged Guanine Base Pairs with Guanine
DNA is constantly exposed to endogenous and exogenous oxidative stresses. Damaged DNA can cause mutations, which may increase the risk of developing cancer and other diseases. G:C-C:G transversions are caused by various oxidative stresses. 2,2,4-Triamino-
Hiroshi Miyazawa +5 more
doaj +1 more source
Identification of a novel cytosolic aldehyde dehydrogenase allele,
This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 (ALDHIAI) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped.
Moore Shelley M +5 more
doaj +1 more source
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources
A Porphyrin-DNA Chiroptical Molecular Ruler With Base Pair Resolution
DNA-based molecular rulers enable scientists to determine important parameters across biology, from the measurement of protein binding interactions, to the study of membrane dynamics in cells.
Jonathan R. Burns +2 more
doaj +1 more source
Quantum Logic Gates Based on DNAtronics, RNAtronics, and Proteintronics
Quantum computers (QCs) adopt an n‐state quantum mechanical system to manipulate the superposition state. However, molecular transistors are not used to build up the quantum logic gate.
Sheh-Yi Sheu, Hua-Yi Hsu, Dah-Yen Yang
doaj +1 more source
Characterization of the trans Watson-Crick GU base pair located in the catalytic core of the antigenomic HDV ribozyme. [PDF]
The HDV ribozyme's folding pathway is, by far, the most complex folding pathway elucidated to date for a small ribozyme. It includes 6 different steps that have been shown to occur before the chemical cleavage.
Dominique Lévesque +2 more
doaj +1 more source
Single nucleotide polymorphisms (SNPs) affect base pair stacking, which is the primary factor for maintaining the stability of DNA. However, the mechanism of how SNPs lead to phenotype variations is still unclear. In this work, we connected SNPs and base
Gen Li +6 more
doaj +1 more source
DFT study on metal-mediated uracil base pair complexes
The most stable of metal-mediated uracil base pair complexes were determined. Method was used density functional theory, B3LYP. The calculations of systems containing C, H, N, O were described by 6-311++G(d,p) and cc-PVTZ basis sets and LANL2DZ and SDD ...
Ayhan Üngördü, Nurten Tezer
doaj +1 more source
The base-pairing ability of the base pair-mimic nucleosides [PDF]
The deoxyadenosine derivative tethering the phenyl group at N6 of deoxyadenosine (A(phe)) was previously found to have a property to stack strongly with adjacent nucleotide bases in a DNA duplex. On the other hand, it was also demonstrated that DNA polymerases selectively incorporated dTTP opposite A(phe) in a template DNA strand.
Shu-Ichi, Nakano +3 more
openaire +2 more sources

