Results 41 to 50 of about 20,403 (100)

Fluorescent nucleobase analogues for base–base FRET in nucleic acids: synthesis, photophysics and applications

open access: yesBeilstein Journal of Organic Chemistry, 2018
Förster resonance energy transfer (FRET) between a donor nucleobase analogue and an acceptor nucleobase analogue, base–base FRET, works as a spectroscopic ruler and protractor.
Mattias Bood   +4 more
doaj   +1 more source

Cooperative base pair melting by helicase and polymerase positioned one nucleotide from each other

open access: yeseLife, 2015
Leading strand DNA synthesis requires functional coupling between replicative helicase and DNA polymerase (DNAP) enzymes, but the structural and mechanistic basis of coupling is poorly understood.
Divya Nandakumar   +2 more
doaj   +1 more source

PP2C – like promoter and its deletion variants are induced by ABA but not by MeJA and SA in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2016
Gene expression is mediated through interaction between cis regulatory elements and its cognate transcription factors. Cis regulatory elements are defined as non-coding DNA sequences that provide the binding sites for transcription factors and are ...
Rajesh eMehrotra   +4 more
doaj   +1 more source

Recognition and Sequencing of Mutagenic DNA Adduct at Single‐Base Resolution Through Unnatural Base Pair

open access: yesAdvanced Science
DNA lesions are linked to cancer, aging, and various diseases. The recognition and sequencing of special DNA lesions are of great interest but highly challenging.
Honglei Wang   +8 more
doaj   +1 more source

Free Solution Assay Signal Modulation in Variable-Stem-Length Hairpin Aptamers

open access: yesACS Omega, 2020
Michael N. Kammer   +4 more
doaj   +1 more source

Base-pair Opening Dynamics of Nucleic Acids in Relation to Their Biological Function

open access: yesComputational and Structural Biotechnology Journal, 2019
Base-pair opening is a conformational transition that is required for proper biological function of nucleic acids. Hydrogen exchange, observed by NMR spectroscopic experiments, is a widely used method to study the thermodynamics and kinetics of base-pair
Seo-Ree Choi   +5 more
doaj  

Replacing thymine with a strongly pairing fifth Base: A combined quantum mechanics and molecular dynamics study

open access: yesComputational and Structural Biotechnology Journal, 2021
The non-natural ethynylmethylpyridone C-nucleoside (W), a thymidine (T) analogue that can be incorporated in oligonucleotides by automated synthesis, has recently been reported to form a high fidelity base pair with adenosine (A) and to be well ...
Mohit Chawla   +4 more
doaj  

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