Results 71 to 80 of about 30,427,296 (288)

Fluctuation-Facilitated Charge Migration along DNA

open access: yes, 2000
We propose a model Hamiltonian for charge transfer along the DNA double helix with temperature driven fluctuations in the base pair positions acting as the rate limiting factor for charge transfer between neighboring base pairs.
A. Garg   +28 more
core   +1 more source

Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion

open access: yesNucleic Acids Research, 2013
The p53 core domain binds to response elements (REs) that contain two continuous half-sites as a cooperative tetramer, but how p53 recognizes discontinuous REs is not well understood. Here we describe the crystal structure of the p53 core domain bound to
Yongheng Chen   +7 more
semanticscholar   +1 more source

Statistical Theory of Force Induced Unzipping of DNA

open access: yes, 2005
The unzipping transition under the influence of external force of a dsDNA molecule has been studied using the Peyrard-Bishop Hamiltonian. The critical force $F_c(T)$ is found to depend on the potential parameters $k$, represents the stiffness of single ...
Anselmetti   +22 more
core   +1 more source

Bubble generation in a twisted and bent DNA-like model [PDF]

open access: yes, 2004
The DNA molecule is modeled by a parabola embedded chain with long-range interactions between twisted base pair dipoles. A mechanism for bubble generation is presented and investigated in two different configurations.
C. R. Calladine   +12 more
core   +3 more sources

Higher order structural effects stabilizing the reverse Watson–Crick Guanine-Cytosine base pair in functional RNAs

open access: yesNucleic Acids Research, 2013
The G:C reverse Watson–Crick (W:W trans) base pair, also known as Levitt base pair in the context of tRNAs, is a structurally and functionally important base pair that contributes to tertiary interactions joining distant domains in functional RNA ...
M. Chawla   +3 more
semanticscholar   +1 more source

Chromatin Structure in the Cellular Slime Mold Dictyostelium discoideum [PDF]

open access: yes, 1978
The structure of Dictyostelium discoideum chromatin has been studied by the following techniques: electron microscopy, staphylococcal nuclease digestion, acrylamide gel electrophoresis, sucrose gradient centrifugation, and melting.
Bakke, Antony C.   +2 more
core  

Pair-Linking for Collective Entity Disambiguation: Two Could Be Better Than All

open access: yes, 2018
Collective entity disambiguation aims to jointly resolve multiple mentions by linking them to their associated entities in a knowledge base. Previous works are primarily based on the underlying assumption that entities within the same document are highly
Han, Jialong   +4 more
core   +1 more source

Frequency and isostericity of RNA base pairs [PDF]

open access: yesNucleic Acids Research, 2009
Most of the hairpin, internal and junction loops that appear single-stranded in standard RNA secondary structures form recurrent 3D motifs, where non-Watson-Crick base pairs play a central role. Non-Watson-Crick base pairs also play crucial roles in tertiary contacts in structured RNA molecules.
Stombaugh, Jesse   +3 more
openaire   +4 more sources

Site-Specific Incorporation of Functional Components into RNA by an Unnatural Base Pair Transcription System

open access: yesMolecules, 2012
Toward the expansion of the genetic alphabet, an unnatural base pair between 7-(2-thienyl)imidazo[4,5-b]pyridine (Ds) and pyrrole-2-carbaldehyde (Pa) functions as a third base pair in replication and transcription, and provides a useful tool for the site-
Rie Kawai   +4 more
doaj   +1 more source

Biomechanics of DNA: rotational oscillations of bases [PDF]

open access: yesКомпьютерные исследования и моделирование, 2011
In this paper we study the rotational oscillations of the nitrous bases forming a central pair in a short DNA fragment consisting of three base pairs.
L. V. Yakushevich
doaj   +1 more source

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