Results 81 to 90 of about 1,688,512 (279)
NMR spectroscopy of the ring nitrogen protons of uracil and substituted uracils; relevance to A ψ base pairing in the solution structure of transfer RNA [PDF]
, 1977 Ralph E. Hurd, Brian R. Reid
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Molecular Oncology, EarlyView.We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park +8 more
wiley +1 more source
ROLE OF DNA SEQUENCES IN GENETIC RECOMBINATION IN THE ISO-1-CYTOCHROME c GENE OF YEAST. II. COMPARISON OF MUTANTS ALTERED AT THE SAME AND NEARBY BASE PAIRS [PDF]
, 1977 C W Moore, Fred Sherman
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Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Synthetic Spectroscopic Models Related to Coenzymes and Base Pairs, VII. Stacking Interactions in tRNA; the „Bend” at Dimethylguanosine [PDF]
, 1970 Hajime Iwamura +2 more
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Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Gasket Assembly for Sealing Mating Surfaces [PDF]
A gasket assembly for securing a pair of surface together wherein an electrically conductive gasket base having a central opening is provided with a pair of layers secured to opposite sides of the gasket base, with the layers being a fusible alloy, a ...
Bryant, Melvin A., III
core +1 more source
Extended Particle Model Based on the Quark Model with an Arbitrary Number of Quark-Anti-Quark Pairs [PDF]
, 1970 Kimio Fujimura, Tsunehiro Kobayashi
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Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
On the Generalization of the Urbaryon Model Based on Lepton-Pairs [PDF]
, 1975 T. Hayashi +3 more
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