Results 131 to 140 of about 28,951,856 (408)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Pairing-based identification schemes [PDF]

open access: yesarXiv, 2005
We propose four different identification schemes that make use of bilinear pairings, and prove their security under certain computational assumptions. Each of the schemes is more efficient and/or more secure than any known pairing-based identification scheme.
arxiv  

A rule of seven in Watson-Crick base pairing of mismatched sequences

open access: yesNature Structural &Molecular Biology, 2012
Sequence recognition through base-pairing is essential for DNA repair and gene regulation, but the basic rules governing this process remain elusive.
I. Cissé, Hajin Kim, T. Ha
semanticscholar   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Pairing Based Cryptography

open access: yes, 2022
In dieser Masterarbeit untersuchen wir Pairings auf elliptischen Kurven, deren Anwendung in der Kryptographie und deren Berechnung. Pairings sind bestimmte bilineare Funktionen zwischen Gruppen, wobei wir solche Abbildungen insbesondere für die Gruppe der Punkte elliptischer Kurven finden können. Beide diese Begriffe werden in dieser Arbeit eingeführt.
openaire   +2 more sources

DNA with Artificial Base Pairs

open access: yesCHIMIA, 2005
The introduction of a single base pair with the electronically complementary base surrogates phenyl- (P) and pentafluorophenyl-deoxyriboside (F5) into DNA oligonucleotides leads to a strong decrease in duplex stability. Longer stretches with alternating P-F5 pairs can lead to duplexes with increased stability as compared to their counterparts
Gérald Mathis, Jürg Hunziker
openaire   +4 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Stable stem enabled Shannon entropies distinguish non-coding RNAs from random backgrounds

open access: yesBMC Bioinformatics, 2012
Background The computational identification of RNAs in genomic sequences requires the identification of signals of RNA sequences. Shannon base pairing entropy is an indicator for RNA secondary structure fold certainty in detection of structural, non ...
Wang Yingfeng   +6 more
doaj   +1 more source

Improved Cycle Sequencing of GC-Rich Templates by a Combination of Nucleotide Analogs

open access: yesBioTechniques, 2000
A common problem in automated DNA sequencing when applying the Sanger chain termination method is ambiguous base calling caused by band compressions.
Michael Motz   +2 more
doaj   +1 more source

Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides.

open access: yesGenes & Development, 2012
An established paradigm in pre-mRNA splicing is the recognition of the 5' splice site (5'ss) by canonical base-pairing to the 5' end of U1 small nuclear RNA (snRNA).
Xavier Roca   +5 more
semanticscholar   +1 more source

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