Results 21 to 30 of about 28,547,466 (259)
An ISFET Microarray Sensor System for Detecting the DNA Base Pairing. [PDF]
Micromachines (Basel), 2021 Deoxyribonucleic acid (DNA) sequencing technology provides important data for the disclosure of genetic information and plays an important role in gene diagnosis and gene therapy.
Sun P, Cong Y, Xu M, Si H, Zhao D, Wu D.
europepmc +2 more sources
Journal of Experimental and Molecular Biology, 2022 In contrast to Watson-Crick (WC) base pairing, Hoogsteen (HG) base pairing involves flipping a purine base 180° between its anti and syn conformation.
Neelabh Datta
doaj +1 more source
LinearPartition: linear-time approximation of RNA folding partition function and base-pairing probabilities [PDF]
Bioinform., 2019 Motivation RNA secondary structure prediction is widely used to understand RNA function. Recently, there has been a shift away from the classical minimum free energy methods to partition function-based methods that account for folding ensembles and can ...
He Zhang +3 more
semanticscholar +1 more source
Base-Pairing and Base-Stacking Contributions to Double-Stranded DNA Formation.
Journal of Physical Chemistry B, 2020 Double-stranded (ds)DNA formation and dissociation are of fundamental biological importance. The negative DNA charge influences the dsDNA stability. However, the base pairing and the stacking between neighboring bases are responsible for the sequence ...
M. Zacharias
semanticscholar +1 more source
Base Pairing and Functional Insights into N3-methylcytidine (m3C) in RNA
bioRxiv, 2020 N3-methylcytidine (m3C) is present in both eukaryotic tRNA and mRNA and plays critical roles in many biological processes. We report the synthesis of the m3C phosphoramidite building block and its containing RNA oligonucleotides.
S. Mao +5 more
semanticscholar +1 more source
Journal of the American Chemical Society, 2020 Allosteric regulation is gaining increasing attention as a basis for production of stimuli-responsive materials in many research areas including DNA nanotechnology.
Takahiro Nakama +3 more
semanticscholar +1 more source
DNA-Mimicking Metal-Organic Frameworks with Accessible Adenine Faces for Complementary Base Pairing. [PDF]
JACS Au, 2022 Chand S +8 more
europepmc +2 more sources
The RNA Base-Pairing Problem and Base-Pairing Solutions. [PDF]
Cold Spring Harb Perspect Biol, 2018 SUMMARYRNA molecules are folded into structures and complexes to perform a wide variety of functions. Determination of RNA structures and their interactions is a fundamental problem in RNA biology. Most RNA molecules in living cells are large and dynamic,
Lu Z, Chang HY.
europepmc +2 more sources
Effect of Molecular Crowding on DNA Polymerase Reactions along Unnatural DNA Templates
Molecules, 2020 Unnatural nucleic acids are promising materials to expand genetic information beyond the natural bases. During replication, substrate nucleotide incorporation should be strictly controlled for optimal base pairing with template strand bases. Base-pairing
Shuntaro Takahashi +2 more
doaj +1 more source
Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]
PLoS Genetics, 2010 The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng +8 more
doaj +1 more source