Results 21 to 30 of about 32,528,266 (371)

Sequence-encoded intermolecular base pairing modulates fluidity in DNA and RNA condensates [PDF]

Nature Communications
Nature uses bottom-up self-assembly to build structures with remarkable complexity and functionality. Understanding how molecular-scale interactions translate to macroscopic properties remains a major challenge and requires systems that effectively ...
Sumit Majumder, Sebastian Coupe, Nikta Fakhri, Ankur Jain   +3 more
doaj   +2 more sources

Base-pairing of uracil and 2,6-diaminopurine: from cocrystals to photoreactivity [PDF]

iScience
Summary: We show that the non-canonical nucleobase 2,6-diaminopurine (D) spontaneously base pairs with uracil (U) in water and the solid state without the need to be attached to the ribose-phosphate backbone. Depending on the reaction conditions, D and U
Tomislav Stolar, Ben K.D. Pearce, Martin Etter, Khai-Nghi Truong, Tea Ostojić, Andraž Krajnc, Gregor Mali, Barbara Rossi, Krešimir Molčanov, Ivor Lončarić, Ernest Meštrović, Krunoslav Užarević, Luca Grisanti   +12 more
doaj   +2 more sources

Force-Field-Dependent DNA Breathing Dynamics: A Case Study of Hoogsteen Base Pairing in A6-DNA. [PDF]

J Chem Inf Model, 2022
Stone SE, Ray D, Andricioaei I.
europepmc   +3 more sources

Correction to 'Thermodynamic stability and Watson-Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect'. [PDF]

Nucleic Acids Res, 2023
europepmc   +3 more sources

How do base-pairing small RNAs evolve? [PDF]

FEMS Microbiology Reviews, 2015
Taylor B. Updegrove, Svetlana A. Shabalina, Gisela Storz   +2 more
openalex   +2 more sources

Schiff base-mediated base pairing [PDF]

Nucleic Acids Symposium Series, 2005
We here present a novel covalently linked base pair via Schiff base formation between 5-formyluracil (fU) and 5-aminocytosine (AmC). The formation of Schiff base remarkably increases thermal stability of the duplex DNA, whereas it completely dissociates upon heating at 90 degrees C. Neither AmC nor fU produces covalent linkage with other natural bases,
Chikara, Dohno, Akimitsu, Okamoto, Isao, Saito   +2 more
openaire   +2 more sources

DNA-Mimicking Metal–Organic Frameworks with Accessible Adenine Faces for Complementary Base Pairing [PDF]

JACS Au, 2022
Santanu Chand, Othman Alahmed, Walaa S. Baslyman, Avishek Dey, Somayah Qutub, Ranajit Saha, Yuh Hijikata, Manal Alaamery, Niveen M. Khashab   +8 more
doaj   +2 more sources

LinearPartition: linear-time approximation of RNA folding partition function and base-pairing probabilities [PDF]

Bioinform., 2019
Motivation RNA secondary structure prediction is widely used to understand RNA function. Recently, there has been a shift away from the classical minimum free energy methods to partition function-based methods that account for folding ensembles and can ...
He Zhang, Liang Zhang, D. Mathews, Liang Huang   +3 more
semanticscholar   +1 more source

Prevalence of small base-pairing RNAs derived from diverse genomic loci.

Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 2020
Small RNAs (sRNAs) that act by base-pairing have been shown to play important roles in fine-tuning the levels and translation of their target transcripts across a variety of model and pathogenic organisms.
Philip P. Adams, G. Storz
semanticscholar   +1 more source

Effect of Molecular Crowding on DNA Polymerase Reactions along Unnatural DNA Templates

Molecules, 2020
Unnatural nucleic acids are promising materials to expand genetic information beyond the natural bases. During replication, substrate nucleotide incorporation should be strictly controlled for optimal base pairing with template strand bases. Base-pairing
Shuntaro Takahashi, Piet Herdwijn, Naoki Sugimoto   +2 more
doaj   +1 more source