Results 41 to 50 of about 117,633 (252)

Exploring potential of i-motif DNA formed in the promoter region of GRIN1 gene for nanotechnological applications

open access: yesResults in Chemistry, 2020
The tandem repeat stretches of cytosine residues fold to construct intercalated motif (i-motif) structures over an acidic pH range. Several advancements have been made to understand the biological role of i-motif DNA.
Swati Chaudhary   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Base‐Filling in Double‐Helical Nucleic Acids

open access: yesChemistryOpen
Base‐filling, i. e., post‐synthetic furnishing of an oligonucleotide scaffold with base moieties or their analogues, is an interesting alternative to the conventional approach of sequential coupling of building blocks (modified or otherwise).
Mark Nana Kwame Afari, Tuomas Lönnberg
doaj   +1 more source

Selecting against accidental RNA interactions

open access: yeseLife, 2016
Random base-pairing interactions between messenger RNAs and noncoding RNAs can reduce translation efficiency.
Meredith Corley, Alain Laederach
doaj   +1 more source

Report on Pairing-based Cryptography

open access: yesJournal of Research of the National Institute of Standards and Technology, 2015
This report summarizes study results on pairing-based cryptography. The main purpose of the study is to form NIST's position on standardizing and recommending pairing-based cryptography schemes currently published in research literature and standardized in other standard bodies. The report reviews the mathematical background of pairings.
Moody, Dustin   +5 more
openaire   +2 more sources

The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2017
The 5-Cl-dU:7-deaza-dA base pair can be a substitute for the dT:dA base pair in an enzymatic replication process of 2 kb DNA.
Eremeeva, Elena   +3 more
openaire   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Cis- and Trans-Encoded Small Regulatory RNAs in Bacillus subtilis

open access: yesMicroorganisms, 2021
Small regulatory RNAs (sRNAs) that act by base-pairing are the most abundant posttranscriptional regulators in all three kingdoms of life. Over the past 20 years, a variety of approaches have been employed to discover chromosome-encoded sRNAs in a ...
Sabine Brantl, Peter Müller
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs. [PDF]

open access: yesPLoS Computational Biology, 2017
Prediction of RNA tertiary structure from sequence is an important problem, but generating accurate structure models for even short sequences remains difficult.
Michael F Sloma, David H Mathews
doaj   +1 more source

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