Results 51 to 60 of about 32,528,266 (371)
Molecules, 2023 5-Amino-1-β-D-ribofuranosylimidazole-4-carboxamide 5′-monophosphate (ZMP) is a central intermediate in de novo purine nucleotide biosynthesis. Its nucleobase moiety, 5-aminoimidazole-4-carboxamide (Z-base), is considered an ambiguous base that can pair ...
Yuhei Nogi +3 more
doaj +1 more source
The base-pairing ability of the base pair-mimic nucleosides [PDF]
Nucleic Acids Symposium Series, 2007 The deoxyadenosine derivative tethering the phenyl group at N6 of deoxyadenosine (A(phe)) was previously found to have a property to stack strongly with adjacent nucleotide bases in a DNA duplex. On the other hand, it was also demonstrated that DNA polymerases selectively incorporated dTTP opposite A(phe) in a template DNA strand.
Shu-Ichi, Nakano +3 more
openaire +2 more sources
Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation
Nature Communications, 2016 Prokaryotic translation initiation involves mRNA-ribosomal RNA base pairing interactions. Here, the authors provide evidence for a similar base pairing interactions occurring between the human h4 mRNA and helix 16 of the small subunit rRNA to position ...
Franck Martin +8 more
doaj +1 more source
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure. [PDF]
, 2013 MicroRNAs (miRNAs) typically downregulate protein expression from target mRNAs through limited base-pairing interactions between the 5' 'seed' region of the miRNA and the mRNA 3' untranslated region (3'UTR). In contrast to this established mode of action,
Doudna, Jennifer A, Mortimer, Stefanie A
core +1 more source
Partition function and base pairing probabilities of RNA heterodimers
Algorithms for Molecular Biology, 2006 Background RNA has been recognized as a key player in cellular regulation in recent years. In many cases, non-coding RNAs exert their function by binding to other nucleic acids, as in the case of microRNAs and snoRNAs.
Stadler Peter F +5 more
doaj +1 more source
Life, 2020 It is possible that early life relied on RNA polymers that served as ribozyme-like catalysts and for storing genetic information. The source of such polymers is uncertain, but previous investigations reported that wet–dry cycles simulating prebiotic hot ...
Tue Hassenkam +3 more
doaj +1 more source
Ground state and glass transition of the RNA secondary structure
, 2006 RNA molecules form a sequence-specific self-pairing pattern at low temperatures. We analyze this problem using a random pairing energy model as well as a random sequence model that includes a base stacking energy in favor of helix propagation.
Bundschuh +31 more
core +1 more source
High Base Pair Opening Rates in Tracts of GC Base Pairs [PDF]
Journal of Biological Chemistry, 1999 Sequence-dependent structural features of the DNA double helix have a strong influence on the base pair opening dynamics. Here we report a detailed study of the kinetics of base pair breathing in tracts of GC base pairs in DNA duplexes derived from 1H NMR measurements of the imino proton exchange rates upon titration with the exchange catalyst ammonia.
U, Dornberger, M, Leijon, H, Fritzsche
openaire +2 more sources
Unconventional superconductivity in iron-base superconductors in a three-band model [PDF]
, 2014 Iron-base superconductors exhibits features of systems where the Fulde-Ferrel-Larkin-Ovchinnikov (FFLO) phase, a superconducting state with non-zero total momentum of Cooper pairs, is actively sought. Experimental and theoretical evidence points strongly
Crivelli, Dawid, Ptok, Andrzej
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro +10 more
wiley +1 more source