Cognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments. [PDF]
Alzheimers Dement (Amst), 2021 Ophey A +30 more
europepmc +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The effect of the monetary base on money supply – Does the quantity of central bank money carry any information? [PDF]
In discussing the transmission mechanism, basic macroeconomics textbooks focus on changes in money supply, which the central bank can control by manipulating the monetary base.
András Komáromi
core
Base rate of ovarian cancer on algorithms in patients with a pelvic mass. [PDF]
Int J Gynecol Cancer, 2020 Rolfsen ALD +3 more
europepmc +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
CONSIDERATIONS REGARDING THE INFLUENCE OF THE BASE LEADING RATE OVER INVESTMENT PROJECTS FINANCED BY EU FUNDS [PDF]
The investment process is a complex economic process that implies risks. Allottingcapital resources in an investment project without using an adequate discount rate of the cashflows, which will take into account the evolution of the base leading rate of ...
Attila Tamas Szora, Iulian Bogdan Dobra
core
Detecting children's true and false denials of wrongdoing: Effects of question type and base rate knowledge. [PDF]
Behav Sci Law, 2020 Domagalski K +4 more
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source