Results 221 to 230 of about 4,826,112 (291)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The Interplay Between Non-Instantaneous Dynamics of mRNA and Bounded Extrinsic Stochastic Perturbations for a Self-Enhancing Transcription Factor. [PDF]

Entropy (Basel)
Cabriel L, Caravagna G, de Franciscis S, Anselmi F, D'Onofrio A.   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Field study on heat transfer performance and thermo-mechanical properties of pre-bored PHC energy pile. [PDF]

Sci Rep
Zhou JJ, Zhang RH, Yu JL, Jin S.
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Clinical performance and occlusal wear of polymer-infiltrated ceramic network and zirconia-reinforced ceramic implant-supported single crowns fabricated via a digital workflow on two titanium implant systems: a 12-month prospective randomized trial. [PDF]

Int J Implant Dent
Bagratuni M, Bruhnke M, Bohner L, Herklotz I, Beuer F, Böse MWH, Pieralli S.   +6 more
europepmc   +1 more source

Resilience enhancement strategies for distribution networks considering the coordination of 5G base stations and multiple flexible resources. [PDF]

Sci Rep
Wang H, Ge J, Zhao Y, Gu J, Li C, Liu C.
europepmc   +1 more source

A Constitutional Rate Base

The University of Chicago Law Review, 1939
openaire   +2 more sources

Effects of prophylactic constant-rate infusion of norepinephrine or phenylephrine on neonatal outcomes during caesarean section. [PDF]

Eur J Med Res
Tao W, Bao J, Wang Q, Xie Y, Li S, Wang Z, Zhu S, Huang L, Yang Y, Xu X, Zhu P, Ding P, Tian J, Liu X, Cao H, Liu W, He S, He W, Zhang Y, Hu X.   +19 more
europepmc   +1 more source

Persistently ambiguous: a taxometric investigation on two groups of suicidal ideation indicators. [PDF]

Front Psychol
Carvalho LF, Machado GM, Pianowski G, Hauck-Filho N, Baptista MN, Grønnerød C.   +5 more
europepmc   +1 more source