Results 211 to 220 of about 2,847,295 (322)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

The 10kb Drosophila virus 28S rDNA intervening sequence is flanked by a disect repeat of 14 base pairs of coding sequence

, 1980
Peter M. M. Rae, Bruce D. Kohorn, Robert Wade   +2 more
openalex   +2 more sources

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Controlling DNA-RNA strand displacement kinetics with base distribution. [PDF]

Proc Natl Acad Sci U S A
Ratajczyk EJ, Bath J, Šulc P, Doye JPK, Louis AA, Turberfield AJ.   +5 more
europepmc   +1 more source

The phylogenetic position ofDictyoglomus thermophilumbased on 16S rRNA sequence analysis [PDF]

, 1993
Christopher Love, Bharat Patel, Wolfgang Ludwig, Erko Stackebrandt   +3 more
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning. [PDF]

Nat Commun
Perez M, Kimoto M, Rajakumar P, Suphavilai C, Peres da Silva R, Tan HP, Ong NTX, Nicholas H, Hirao I, Chew WL, Nagarajan N.   +10 more
europepmc   +1 more source

A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation [PDF]

, 1990
Brian P. Sorrentino, Paul A. Ney, David M. Bodine, A.W. Nienhius   +3 more
openalex   +1 more source

Schauder bases and Köthe sequence spaces [PDF]

Transactions of the American Mathematical Society, 1968
J. R. Retherford, Ed Dubinsky
openaire   +2 more sources