Results 291 to 300 of about 31,885,483 (388)

Base sequence, local helix structure, and macroscopic curvature of A-DNA and B-DNA.

, 1986
Chih‐Hang Tung, Stephen C. Harvey
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

In silico development of HASDI-G2 as a novel agent for selective recognition of the DNA sequence. [PDF]

Sci Rep
Zaremba A, Zaremba P, Zahorodnia S.
europepmc   +1 more source

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

Nature, 2000
C. Stover, X. Pham, A. Erwin, S. Mizoguchi, P. Warrener, M. Hickey, F. Brinkman, W. O. Hufnagle, D. J. Kowalik, Lagrou Mj, R. Garber, L. Goltry, E. Tolentino, S. Westbrock-Wadman, Ying Yuan, L. L. Brody, S. Coulter, K. Folger, A. Kas, K. Larbig, R. Lim, Kelly D. Smith, D. Spencer, Gane Ka-Shu Wong, Z. Wu, I. Paulsen, J. Reizer, M. Saier, R. Hancock, S. Lory, M. Olson   +30 more
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Solidification Sequence and Carbide Precipitation in Ni-Base Superalloys Ιn718, In625 and In939

High Temperature Materials and Processes, 2005
Formenti, A., Eliasson, A., Mitchell, A., Fredriksson, H.   +3 more
doaj   +1 more source

TopoQual polishes circular consensus sequencing data and accurately predicts quality scores. [PDF]

BMC Bioinformatics
Weerakoon M, Lee S, Mitchell E, Heaton H.   +3 more
europepmc   +1 more source

SixSchizosaccharomyces pombetRNA genes including a gene for a tRNA^Lyswith an intervening sequence which cannot base-pair with the anticodon

, 1983
Vera Gamulin, Jen-i Mao, Bernd Appel, Martin Sumner-Smith, Fumiaki Yamao, Dieter Söll   +5 more
openalex   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source