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Sequencing-Based Typing of HLA

2007
Human leukocyte antigen (HLA) typing is largely performed by use of PCR-based techniques in patients that require stem cell transplantation. In this chapter, HLA typing by sequencing-based typing techniques is described.
Berthold, Hoppe, Abdulgabar, Salama
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The Evolution of Base Sequences in Polynucleotides

1965
Publisher Summary This chapter discusses the real problems in the evolution of organisms and the understanding of the evolution at other levels of the organization that suggests comparative examination of the chemical structure of the genes. In addition, these discussions of nucleotide sequence leads to a consideration of a variety of subjects, such ...
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Bases and Basic Sequences

2016
In this chapter we are going to introduce the fundamental notion of a Schauder basis of a Banach space and the corresponding notion of a basic sequence. One of the key ideas in the isomorphic theory of Banach spaces is to use the properties of bases and basic sequences as a tool to understanding the differences and similarities between spaces.
Fernando Albiac, Nigel J. Kalton
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Sequence-Based Prediction of Protein Solubility

Journal of Molecular Biology, 2012
In order to investigate the relationship between the thermodynamics and kinetics of protein aggregation, we compared the solubility of proteins with their aggregation rates. We found a significant correlation between these two quantities by considering a database of protein solubility values measured using an in vitro reconstituted translation system ...
Agostini, F.   +2 more
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Sequence-Based Identification of Legionella

2012
Legionella strains are considered biologically inert with respect to traditional identification schemes. Various phenotypic alternatives have been attempted but all have lacked resolution as additional species have been added to what is proving to be a large genus.
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Sequence-Based Markers

2015
Marker-assisted selection (MAS) has revolutionized plant and animal breeding activities. MAS is based on DNA markers, which facilitate gene/QTL identification and mapping and gene/QTL transfer, and has many other applications. Some of the important issues concerning marker systems relate to their abundance, genome-wide distribution, cost and effort for
B. D. Singh, A. K. Singh
openaire   +1 more source

Filtering Bio-sequence Based on Sequence Descriptor

2006
Study on biological sequence database similarity searching has received substantial attention in the past decade, especially after the sequencing of the human genome. As a result, with larger and larger increases in database sizes, fast similarity search is becoming an important issue.
Te-Wen Hsieh   +2 more
openaire   +1 more source

Sequence Comparisons and Sequence-Based Database Searches

2018
The comparison of protein and DNA sequences is an important analytical method of applied bioinformatics. The annotations of new nucleotide and protein sequences, construction of model structures for proteins, design and analysis of expression studies, and a variety of other bioinformatic and biological experiments are all based on these analyses ...
Paul M. Selzer   +2 more
openaire   +1 more source

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