Results 301 to 310 of about 31,885,483 (388)

Simulating the Helicase Enzymatic Action on ds-DNA: A First-Principles Molecular Dynamics Study. [PDF]

ACS Omega
Rodriguez-Leon AI, Ordóñez C, Santamaria R.   +2 more
europepmc   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

The complete mitochondrial genome analysis of <i>Haemaphysalis hystricis</i> Supino, 1897 (Ixodida: Ixodidae) and its phylogenetic implications. [PDF]

Open Life Sci
Li ZB, Xiang M, Yang T, Hu H, Shu M, Huang CQ.   +5 more
europepmc   +1 more source

4822606 Immunosuppressive synthetic peptides and analogs thereof based on retroviral envelope sequences

, 1989

openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Mammalian piRNA target prediction using a hierarchical attention model. [PDF]

BMC Bioinformatics
Zhang T, Chen L, Zhu H, Wong G.
europepmc   +1 more source

Plasmid pLS1-encoded RepA protein regulates transcription from repAB promoter by binding to a DNA sequence containing a 13-base pair symmetric element.

, 1990
Gloria del Solar, José Pérez-Martı́n, Manuel Espinosa   +2 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Guanine Amine Derivatives Promote Forming a Base-Vacancy-G Quadruplex Structure. [PDF]

ACS Omega
Liang B, Zhu J, Yu H, Wu J, Ouyang F, Liu Y.   +5 more
europepmc   +1 more source

Origin and evolution of retroelements based upon their reverse transcriptase sequences.

, 1990
Yue Xiong, Thomas H. Eickbush
openalex   +1 more source