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Sequence-Based Markers

2015
Marker-assisted selection (MAS) has revolutionized plant and animal breeding activities. MAS is based on DNA markers, which facilitate gene/QTL identification and mapping and gene/QTL transfer, and has many other applications. Some of the important issues concerning marker systems relate to their abundance, genome-wide distribution, cost and effort for
B. D. Singh, A. K. Singh
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DNA-Based Sequencing Assays

2018
Modern cytopathologists need to incorporate molecular testing into their clinical practice and be able to translate molecular assays into patient care. The detection of genomic alterations may not only refine uncertain morphological diagnoses but may also provide crucial theranostic information.
Pisapia, Pasquale   +4 more
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Sequence-based MicroRNA Clustering

Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies, 2016
MicroRNAs (miRNAs) play important roles in post-transcriptional gene regulation. Altogether, understanding integrative and co-operative activities in gene regulation is conjugated with identification of miRNA families. In current applications, the identification of such groups of miRNAs is only investigated by the projections of their expression ...
Mahinur S. Akkaya   +2 more
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Filtering Bio-sequence Based on Sequence Descriptor

2006
Study on biological sequence database similarity searching has received substantial attention in the past decade, especially after the sequencing of the human genome. As a result, with larger and larger increases in database sizes, fast similarity search is becoming an important issue.
Jen-Peng Huang   +2 more
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The Evolution of Base Sequences in Polynucleotides

1965
Publisher Summary This chapter discusses the real problems in the evolution of organisms and the understanding of the evolution at other levels of the organization that suggests comparative examination of the chemical structure of the genes. In addition, these discussions of nucleotide sequence leads to a consideration of a variety of subjects, such ...
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Sequence Comparisons and Sequence-Based Database Searches

2018
The comparison of protein and DNA sequences is an important analytical method of applied bioinformatics. The annotations of new nucleotide and protein sequences, construction of model structures for proteins, design and analysis of expression studies, and a variety of other bioinformatic and biological experiments are all based on these analyses ...
Richard J. Marhöfer   +2 more
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Base sequences, complementary ternary sequences, and orthogonal designs

Journal of Combinatorial Designs, 1996
Summary: We construct several new families of orthogonal designs related to one of the weighing matrix conjectures. We also construct some new complementary quadruples \((A;B;C;D)\) of \(\{0,\pm 1\}\)-sequences of length \(n\) and total weight \(w\), denoted as \(\text{CTQ} (n,w)\).
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Sequencing-based analysis of microbiomes

Nature Reviews Genetics
Microbiomes occupy a range of niches and, in addition to having diverse compositions, they have varied functional roles that have an impact on agriculture, environmental sciences, and human health and disease. The study of microbiomes has been facilitated by recent technological and analytical advances, such as cheaper and higher-throughput DNA and RNA
Yishay Pinto, Ami S. Bhatt
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Base excision sequence scanning

Nature Biotechnology, 1997
Les M. Hoffman, Gregory A. Hawkins
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