Results 61 to 70 of about 8,322,522 (296)

Prediction of budburst, blooming and harvesting of apple trees using thermal sum models in mild winter conditions [PDF]

open access: yesBrazilian Journal of Biology
Even though thermal sum models have become important tools to predict phenological stages and apples’ harvest, there have been many questions not only about which model to choose but also about their precision.
L. O. D. Marques   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Cardinal temperatures variability within a tropical japonica rice diversity panel

open access: yesPlant Production Science, 2018
Air temperature is one of the most critical climatic factors controlling rice growth, development, and production in current and future climatic scenarii predicting increasingly frequent situations of extreme and/or fluctuating temperatures.
Lauriane Rouan   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cyclic crack growth behaviour of two nickel base turbine disc alloys

open access: yes, 1998
The high temperature fatigue crack growth behaviour of the nickel base superalloys Alloy 718 and Rene 95 (specimen thickness = 4.1 mm) were investigated and compared with each other.
Doruk, M, Arslan, Gökhan, Arslan, G
core   +1 more source

Emissão de folhas e início de acumulação de amido em raízes de uma variedade de mandioca em função da época de plantio Leaf emergence and beginning of starch accumulation in roots of a cassava variety as a function of planting date

open access: yesCiência Rural, 2007
O número de folhas acumulado (NF) na haste principal está associado com o aparecimento de vários estádios de desenvolvimento da cultura da mandioca. O início de acumulação de amido (IAA) nas raízes tuberosas da mandioca marca o início da translocação dos
Alfredo Schons   +4 more
doaj   +1 more source

Analysis of Copernicus’ ERA5 Climate Reanalysis Data as a Replacement for Weather Station Temperature Measurements in Machine Learning Models for Olive Phenology Phase Prediction

open access: yesSensors, 2020
Knowledge of phenological events and their variability can help to determine final yield, plan management approach, tackle climate change, and model crop development.
Noelia Oses   +5 more
doaj   +1 more source

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