Results 31 to 40 of about 5,534,118 (380)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Implementation of Basel III capital standards and challenges of global economic crisis [PDF]

open access: yesMegatrend Revija, 2015
Implementation of the standards of the Basel Committee on Banking Supervision is an important step towards improving banking. The author seek to illuminate the importance and necessity of introducing new Basel III capital standards, Basel Committee on ...
Ljubić Marijana
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Did Bank Capital Regulation Exacerbate the Subprime Mortgage Crisis?

open access: yesDiscrete Dynamics in Nature and Society, 2009
This contribution is the second in a series of papers on discrete-time modeling of bank capital regulation and its connection with the subprime mortgage crisis (SMC). The latter was caused by, amongst other things, the downturn in the U.S. housing market,
M. A. Petersen   +4 more
doaj   +1 more source

Basel III countercyclical capital rules: implications for South Africa

open access: yesSouth African Journal of Economic and Management Sciences, 2012
The financial crisis has been blamed on many entities, institutions and individuals as well as the Basel II accord which had just begun to be implemented globally when the crisis erupted. The criticisms resulted in the construction of Basel III, a series
Gary Wayne van Vuuren
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

MARKET REACTION TO THE IMPLEMENTATION OF BASEL CAPITAL IN SOUTH AFRICAN BANKS: EVENT STUDY APPROACH

open access: yesThe International Journal of Banking and Finance
This study investigated the stock market reaction and the effect of the implementation of Basel II and Basel III on the stock returns of South African banks.
Damilola Oyetade   +1 more
doaj   +1 more source

The effect of stressed economic conditions on credit risk in Basel II

open access: yesSouth African Journal of Economic and Management Sciences, 2011
The robustness of the Basel II accord in protecting banks during volatile economic periods has been challenged in the ongoing credit crisis. In particular, advanced approaches to measuring and managing credit risk have drawn criticism for being both ...
Ja'nel Esterhuysen   +2 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The treatment of SMEs loans in the New Basel Capital Accord: some evaluations

open access: yesPSL Quarterly Review, 2012
In April 2003 the Basel Committee on Banking Supervision issued a third consultative paper on the new Basel Capital Accord (Basel II). The document contains substantial changes with respect to the previous proposal of January 2001, on which improvements
Fabrizio Fabi   +2 more
doaj   +1 more source

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