Results 141 to 150 of about 2,517,057 (344)

Glomerular Basement Membrane Protein Expression and the Diagnosis and Prognosis of Autosomal Dominant Alport Syndrome

open access: yesKidney Medicine, 2019
Alport syndrome is a hereditary glomerular nephritis associated with hearing loss and eye abnormalities and is classified as X-linked Alport syndrome, autosomal recessive Alport syndrome, and autosomal dominant Alport syndrome.
Taro Akihisa   +12 more
doaj   +1 more source

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

open access: yesAdvanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike   +3 more
wiley   +1 more source

Identification and characterization of agrin in "Caenorhabditis elegans" [PDF]

open access: yes, 2006
Agrin is a large basement membrane (BM) proteoglycan expressed in many tissues in vertebrates, with particularly important function at the neuromuscular junction (NMJ) where it clusters acetylcholine receptors (AChRs) and maintains structural stability ...
Hrus, Ana
core   +1 more source

The Effect of Detergents on the Basement Membrane Complex of a Biologic Scaffold Material

open access: yesActa Biomaterialia, 2013
The basement membrane complex (BMC) is a critical component of the extracellular matrix (ECM) that supports and facilitates the growth of cells. This study investigates four detergents commonly used in the process of tissue decellularization and their ...
D. Faulk   +7 more
semanticscholar   +1 more source

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann   +9 more
wiley   +1 more source

Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes

open access: yes, 2010
Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
core  

Nanoscale protein architecture of the kidney glomerular basement membrane

open access: yeseLife, 2013
In multicellular organisms, proteins of the extracellular matrix (ECM) play structural and functional roles in essentially all organs, so understanding ECM protein organization in health and disease remains an important goal.
H. Suleiman   +6 more
semanticscholar   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto   +6 more
wiley   +1 more source

The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo

open access: yesJournal of Cell Biology, 2013
Localized activation of netrin signaling induces focused F-actin formation and the protrusive force necessary for physical displacement of basement membrane during cell transmigration.
Elliott J. Hagedorn   +7 more
semanticscholar   +1 more source

ITGAM-mediated macrophages contribute to basement membrane damage in diabetic nephropathy and atherosclerosis

open access: yesBMC Nephrology
Background Diabetic nephropathy (DN) and atherosclerosis (AS) are prevalent and severe complications associated with diabetes, exhibiting lesions in the basement membrane, an essential component found within the glomerulus, tubules, and arteries.
Yude Lou   +6 more
doaj   +1 more source

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