Results 121 to 130 of about 2,517,057 (344)
Advanced Healthcare Materials, EarlyView.An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone +4 more
wiley +1 more source
Basement membrane proteoglycans and development
, 1993 Basement membrane proteoglycans and development. Basement membranes contain distinct collagen, glycoprotein and proteoglycan species, and these exhibit considerable heterogeneity in isoform or type when different tissue types are compared.
Couchman, John R. +5 more
core +1 more source
High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations [PDF]
, 1988 Thin and ultrathin cryosections of mouse cornea were labeled with affinity-purified antibodies directed against either laminin, its central segments (domain 1), the end of its long arm (domain 3), the end of one of its short arms (domain 4), nidogen, or ...
Engel, Jürgen +5 more
core +1 more source
Invadopodia and basement membrane invasion in vivo
Cell Adhesion & Migration, 2014 Over 20 years ago, protrusive, F-actin-based membrane structures, termed invadopodia, were identified in highly metastatic cancer cell lines. Invadopodia penetrate artificial or explanted extracellular matrices in 2D culture conditions and have been ...
Lauren R. L. Lohmer +3 more
semanticscholar +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Architecture of the Basement Membrane and the Mouse Cornea
, 1987 Thin and ultrathin cryosections of mouse cornea were labeled with affinity-purified antibodies directed against either laminin, its central segments (domain 1), the end of its long arm (domain 3), the end of one of its short arms (domain 4), nidogen, or ...
Schittny, Johannes
core
Cellular and Molecular Mechanisms regulating Cell Proliferation during the Forebrain Development of the Mouse [PDF]
, 2005 The predominant precursor cell type during cortical neurogenesis are radial glia cells, which receive extrinsic and intrinsic signals that might influence cell proliferation and neurogenesis.
Haubst, Nicole, Haubst, N.
core
Basement membranes at a glance
Journal of Cell ScienceABSTRACT Basement membranes (BMs) underlie or surround most tissues. They are formed of secreted proteins that associate with cell surfaces and are the most ancient animal extracellular matrix. Laminin and collagen IV are core components that polymerize into self-associating networks, providing BMs with an organizing scaffold and tensile
Rachel Lennon, David R. Sherwood
openaire +2 more sources
Journal of Cell Biology, 1988 We have defined a signal responsible for the morphological differentiation of human umbilical vein and human dermal microvascular endothelial cells in vitro.
Yasuo Kubota +3 more
semanticscholar +1 more source
The Mayo Clinic consensus report on membranous nephropathy; a promising step toward better treating the disease [PDF]
Journal of NephropharmacologyMembranous nephropathy is an immune complex disease caused by subepithelial deposits. The pathological manifestations of membranous nephropathy are considered by the creation of immune complexes in the epithelial cells of the glomerular basement membrane.
Samaneh Zandifar +3 more
doaj +1 more source