Results 41 to 50 of about 250 (233)

Perspectiva de género en el abordaje de cambio climático y salud

Práctica Familiar Rural
La intensidad y devastación de los eventos climáticos del Siglo XXI incrementan la vulnerabilidad de personas con problemáticas sociohistóricas preestablecidas. Los impactos de cambio climático en salud no son lineales, se producen de forma diferenciada
Mónica Izurieta-Guevara
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

LITERATURA INFANTIL Y JUVENIL COMO HERRAMIENTA DE PENSAMIENTO CRÍTICO Y RESILIENCIA EMOCIONAL FRENTE AL ODIO Y LA VIOLENCIA. REVISIÓN SISTEMÁTICA DE ESTUDIOS SOBRE INFANCIA Y ADOLESCENCIA

Anuario de Investigación en Literatura Infantil y Juvenil
Este estudio analiza el papel del pensamiento reflexivo y crítico como mecanismo de resiliencia frente a la violencia y el odio en niños y adolescentes.
Sergio Colado García
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Modelos de aprendizaje automático para predecir la durabilidad del hormigón ante el ingreso de cloruros

Revista Odigos
La presente investigación tiene como objetivo analizar las aplicaciones recientes de modelos de aprendizaje automático, enmarcados dentro de la inteligencia artificial, para predecir el ingreso de cloruros en estructuras de hormigón y su impacto en la ...
Mohammadfarid Alvansazyazdi, Milton Altamirano Pazmiño, Natali Lascano Robalino, Nelson Salgado Reyes   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Circularidad como alternativa sostenible en la autoconstrucción de viviendas en zonas vulnerables de Latinoamérica

Revista de Arquitectura (Bogotá)
Este estudio evalúa la viabilidad económica y ambiental de incorporar subproductos derivados de residuos de construcción y demolición y materiales reciclados en la construcción de cerramientos de viviendas sociales en zonas vulnerables.
Patricia González-Vallejo, Marta Edith Yajnes, Susana Inés Caruso, Claudia Marcela Muñoz-Sanguinetti   +3 more
doaj   +1 more source