Results 111 to 120 of about 1,150,117 (291)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI) [PDF]
, 2017 Aims This study aimed to assess functional course in elderly patients undergoing transcatheter aortic valve implantation (TAVI) and to find predictors of functional decline.
Bischoff, Seraina +12 more
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Atención PrimariaResumen: Objetivos: Evaluar el efecto de una intervención de terapia ocupacional en usuarios diagnosticados recientemente de síndrome del declive, con una disminución en el índice de Barthel y/o Lawton en el último mes y susceptible de mejora según ...
Gemma Riera Arias +5 more
doaj +1 more source
Criterion-Related Validity of the Children\u27s Occupational Performance Questionnaire [PDF]
, 2015 This study examined concurrent, criterion-related validity of a new measure of occupational performance for children, the Children’s Occupational Performance Questionnaire (COP-Q).
Zukowski, Kelsey
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
FUNCTIONAL PERFORMANCE IN BASIC ACTIVITIES OF DAILY LIVING IN CHILDREN WITH VISUAL IMPAIRMENT
, 2021 La vison es uno de los sentidos más importantes en el desarrollo normal de un niño. Cuando esta vía sensorial se ve comprometida, el niño puede tener dificultades en el desarrrollo neuropsicomotor, en las relaciones familiares e incluso en las habilidades de la vida diaria.
Santos, Marcela Aparecida +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
South African Journal of Physiotherapy, 2011 A stroke can affect individuals at the levels of impairment, activity and participation. The aim of this study is to determine the activity limitations of stroke patients receiving rehabilitation at out-patient Community health Centres (ChCs). A
A. Rhoda, R. Mpofu, W. De Weerdt
doaj +1 more source
Development and validation of the Total Dyspnea Scale for Cancer Patients [PDF]
, 2019 学位記番号 ...
橋本, 晴美 +2 more
core +2 more sources