Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Mass screening for low bone density using basic check-up items
Given the severe impact of low bone density (LBD) on public health, and to avoid the potential damage of X-rays-based bone density measurements, this study aimed to develop a scoring system for the mass screening for LBD in women aged 50 years or older ...
Wanmin Lian +7 more
core
Initiation of breeding programs for three species of Corymbia: Introduction and provenances study
The objective of this study was to establish populations to start the breeding program of three species of Corymbia that are not widely planted in Brazil yet.
Marcio J. Araujo +3 more
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
El objetivo del trabajo fue evaluar tensiones de crecimiento en Eucalyptus dunnii y determinar el efecto de las propiedades físicas de la madera sobre esta variable. Se muestrearon 45 árboles de un ensayo de 19 años situado en la provincia de Corrientes,
Mariano Hernández +2 more
doaj
Correlações entre algumas propriedades físicas, características químicas e anatômicas da madeira de Luehea divaricata Mart. Malvaceae (Tiliaceae). Correlations among some physical properties, chemical and anatomical features in the wood of Luehea divaricata Mart. Malvaceae (Tiliaceae). [PDF]
Objetivou-se caracterizar a densidade básica, retrações lineares e volumétrica e teores de extrativos, lignlina e holocelulose, no sentido medula-casca da madeira de Luehea divaricata, bem como investigar as correlações existentes entre as ...
Eduardo Luiz LONGUI +4 more
doaj
A ultra-estrutura e a composição química da madeira, bem como suas propriedades físicas e mecânicas, variam significativamente entre espécies, entre árvores de uma mesma espécie e, mesmo, entre diferentes partes de uma mesma árvore.
José Tarcísio da Silva Oliveira +1 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
El raleo tiene implicancias económicas y técnicas tanto para producción forestal como para la actividad industrial. En el presente estudio se realizó la evaluación de un ensayo de intensidad de raleo en E.
Sandro Díaz Bravo +4 more
doaj
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source

